Team:NTU-Singapore/Notebook/Brainstorming

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 Brainstorming Ideas

Health & medicine

 * Create an insulin delivery system which response to low glucose level or time controlled release


 * Vitamin synthesis?


 * Hinder carcinogenics
 * Maslinic acid (olive skin)-tritrepenoid compound
 * Can we study anti-tumoral and apoptotic effect of this compound?
 * E coli to interfere in the carcinogenic pathways
 * Mimic the maslinic effect to the carcinogenic cells?
 * Surface markers?


 * Trap parasites in host cells by disabling the protease
 * Can we remove the trap parasites?
 * Terminate parasites?


 * Genetic modified bacteria that have anticoagulant properties.


 * Eczema relief


 * Bacteria to treat gangrene
 * To eat up dead tissues
 * Bacteria to deliver growth factors


 * Collagen producing bacteria


 * Bacteria that absorbs cholesterol


 * Constipation pill


 * Synthesis specific growth factors


 * Bacteria that produce PDGF


 * Using bacteria to breakdown blockage in blood vessels


 * Malaria vaccine
 * Forcibly expresses a certain gene and create a vaccine against it
 * Proof of concept


 * Cancer treatment - colon cancer(CA marker)
 * Fusion protein to signal the expression of perforin (e coli as NKC)


 * Streptococcus vaccine


 * p-Falciparum gene expression stabilization for malaria


 * Intestinal vaccine delivery


 * Bacteria to target the larvae


 * To separate Tamoxifen (possibly a chiral drug) by uptake the drugs into modified E Coli and bind it to the receptor inside the bacteria.

Biosensor

 * Biosensor that sense the present of allergen and release drugs to prevent allergenic response


 * Mimic allergy response-to determine allergen?


 * Fingerprint detection


 * Can cells response to magnetic fields?
 * Bird GPS ??
 * Magnetic field biosensor


 * Biosensor to detect cancer

Environmental

 * E coli to detect toxins in food and flu strain in animals.


 * Biomask
 * For absorption


 * Create a water purifying system that recognize and trap toxic
 * to uptake salt and others- sea water purification


 * Bacteria producing water for the use of photosynthesis so that plants can grow well in dry area
 * Is it possible to construct water using certain metabolism pathway?

Signalling

 * Multi-color display according to inputs
 * to improve signal inputs
 * DNA methylation as memory storage
 * suffocate the cells
 * baccine
 * To construct guiding E Coli that guide pathogenic bacteria to a region of toxin/UV light.

Application

 * bacterial barometer
 * fill up crack
 * dust repel
 * microscopic spring-using spirobac
 * To construct a Sound sensing bacteria

Modeling

 * modeling the trend of evolution of flu viruses

Bioproduction

 * Methanol in E-coli

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