Team:Groningen/Brainstorm

Environment

 * 1) Uptake, conversion or binding of CO2
 * 2) Cleanup of contamination (water-repellent)
 * 3) Biofuels
 * 4) *(Ligno) cellulose,
 * 5) *Hydrogen
 * 6) *Rocket fuel
 * 7) *Carbon chain production
 * 8) Cigarette smoke dissolving bacteria
 * 9) Biological filter
 * 10) *Toxins and detoxification
 * 11) *Dust/Fine particles

Appliances

 * 1) Clock,,
 * 2) *Seasons
 * 3) *Time
 * 4) * Growth cycle
 * 5) Sound
 * 6) *Detection of, or reaction to radiosignal/antenna
 * 7) *Production (need for very sensitive recorders)
 * 8) Roll the dice – seven is the lucky number!
 * 9) Ambilight (look at Philips for inspiration)
 * 10) Bacteria in motion
 * 11) *Ion motor
 * 12) *Spinning bacteria
 * 13) *Buoyancy
 * 14) Sensors
 * 15) *Pressure
 * 16) *Blood sugar level
 * 17) *Temperature<FONT SIZE="-1"></FONT></SUP>
 * 18) *Smell (detection of spoilage in foods)
 * 19) *TNT, “Improvised explosive device”
 * 20) *Anthrax
 * 21) Biological Lubricant
 * 22) Hydraulics
 * 23) *Uptake of water to increase leverage

Electricity

 * 1) Electrical discharge<FONT SIZE="-1"></FONT></SUP>
 * 2) Solar power cells<FONT SIZE="-1"></FONT></SUP>
 * 3) Magnetic bacteria
 * 4) *NMR/MRI Magnetosome
 * 5) *Compass
 * 6) *Magnetic detection
 * 7) Electronic circuits (on/off)

Medical

 * 1) Recognition and elimination of cancer cells
 * 2) Medicine production
 * 3) * Vaccin<FONT SIZE="-1"></FONT></SUP>
 * 4) Tissue regeneration
 * 5) * Secretion of growthfactors
 * 6) Anthrax system
 * 7) Fat eating bacteria
 * 8) *Fat uptake like fat cells
 * 9) *Eating plaques

Food

 * 1) Milk bacteria (GRAS)
 * 2) *Probiotics<FONT SIZE="-1">,</FONT></SUP>
 * 3) *Prebiotics
 * 4) Enhancing the speed of beer brewing<FONT SIZE="-1"></FONT></SUP>.
 * 5) Improvement of bacterial smell
 * 6) Improvement of taste
 * 7) To let bacteria make additives (taste, smell and colour) for use in food industry
 * 8) To let bacteria make additives (e.g. vitamins)<FONT SIZE="-1">,</FONT></SUP>

Material synthesis

 * 1) Making fibers/polymers
 * 2) Multistep synthesis with bacteria
 * 3) Biosynthesis in general
 * 4) *Making ureum out of simple components
 * 5) *Ureum survival
 * 6) *Nitrogen binding bacteria<FONT SIZE="-1"></FONT></SUP>
 * 7) Nitrogen binding plants with tumor inducing factor

Structure

 * 1) Orbs (spheres)
 * 2) Cells that make a lot of vesicles
 * 3) Stable structure made out of bacteria<FONT SIZE="-1"></FONT></SUP>
 * 4) Crowd control
 * 5) Biofilm, colaboration between different kinds of bacteria (in a controlled way)

Signals/communication

 * 1) Signal transduction
 * 2) Communication between cells
 * 3) Switch to secundair products

New Biobricks

 * 1) Tumor inducing plasmid
 * PNA
 * 1) NICE
 * 2) Clostridium spp; butanol production system<FONT SIZE="-1"></FONT></SUP>
 * 3) Magnetosome

Misc.

 * 1) Evolution
 * 2) * Bacteria that can absorb all DNA and try to use it
 * 3) * New life/"Intelligent design"
 * 4) Ordening of DNA in the cell (index)
 * 5) Clonebots
 * 6) Forensic applications
 * 7) Enlarging biodiversity

Downsizing to five main interest area's

 * 1) Sensors
 * 2) Evolution<FONT SIZE="-1">,,,,,</FONT></SUP>.
 * 3) Growth Timer
 * 4) Magnetic bacteria
 * 5) Movement<FONT SIZE="-1"></FONT></SUP>

Down to three

 * 1) Rainbow bacteria
 * 2) Growth Timer
 * 3) Buoyant bacteria (purification, etc.)<FONT SIZE="-1"></FONT></SUP>

Down to two

 * 1) Glucose Sensing
 * 2) Buoyant bacteria (purification, etc.)<FONT SIZE="-1"></FONT></SUP>

The Final Project

 * 1) EnvironMetal/Buoyant bacteria (purification, etc.)<FONT SIZE="-1">,,,</FONT></SUP>

Modelling
Also see our brainstorm of ideas on modelling!

=List of Demands and wishes=

In order to be able to make a choice from the, in the beginning, almost endless list of possible project we made a list of demands and wishes. This list allows to choose a project which is not only fun but also realistic and doable in the time we had untill the jamboree. It works as a guide and is used often in design processes.

 Demands 
 * Labwork is feasible in 3 month with 8 students.
 * Modelling feasible in 3 months with 3 students.
 * Everyone has to agree with the idea
 * Financially feasible with a budget of 31.170,00 euro of which 8000 euros used for labwork.
 * A new concept, not yet done before in this way, either the iGEM or in the synthetic biology
 * Meets the criteria of iGEM
 * Materials have to be attainable, either via the RuG or able to order in.
 * Parameters for modelling have to be known, or available or attainable.
 * Knowledge about the genes that we are using has to be available.

 Wishes 
 * Not too complicated, not too many genes or gene clusters
 * Has to have an application
 * Using BioBricks that are easy to obtain, preferable available at the RuG.
 * Preferably knowledge on the host, genes and/or end products has to be available at the RuG
 * Some students in the team have experience working with the host.
 * It is possible to find sponsoring for this project.