Team:Newcastle/Meetings/29 June 2009

Internal Meeting 29 June 2009

 * Chair: Hanny
 * Students: James, Jane, Mathew, Goksel

Action Points of the Meeting

 * Assess action points from the last meetings and comment on progress
 * Discuss ideas and thoughts on the Edinburgh UK get-together
 * Raise any issues or questions.

Minutes of the Meeting

 * Assessment of Action Points
 * Model of Metal Intake
 * James has done some of the work but needs more help from biologists!
 * It was discussed that we first of all need to model cadmium only and THEN we can consider other metals - start from the basics.
 * Need to find out how much cadmium binds to the promoter/protein per second
 * Need to measure how much protein is expressed by promoter activation
 * Using this data, work out how much cadmium is taken in by the metallothionein
 * It was decided that the whole team (students) should meet up after lab sessions to work together on getting relevant data and get this model working.
 * We need TWO models - 1) A model for Bacillus subtilis response to cadmium in different scenarios and 2) A model for cadmium influx in B. subtilis
 * Model sinI operon
 * Goksel has made model based on a paper on stochastic switches without changing parameters.
 * Question: Should we leave the model sequence as it is?
 * Model comK sequence
 * Jane has done model based on given equations on paper
 * Not quite sure on the layout of the model (in diagram structure)
 * Can now study CellML
 * Promoter Library
 * Program and task carried out by Jen
 * Prioritise BioBricks
 * Ongoing process
 * Meeting up outside of lab hours to 'map' out project, decide on the BioBricks and design them (along with DNA sequences)
 * Need tutorial on Sequentia
 * Coding in J-Sim
 * Ongoing
 * Write up about Cadmium and the Environment
 * Information has been researched and written into paragraphs
 * Information could be re-written and tidied
 * Decide on Awards
 * Gold Award!
 * Our project fits into the Environmental project strand
 * Wiki, Presentation, Poster
 * Lab Space (Rotas)
 * Decided in meeting that because there is currently six of us, 2 groups of three will start off
 * These groups of three consist of one biologist and two non-biologists
 * Once others come back, may go into pairs
 * External Wiki photos to be uploaded
 * Goksel has uploaded some photographs of Newcastle onto internal wiki
 * CCS template issues on Firefox/Safari/Some versions of IE, etc
 * James has sorted the problem - it turned out to be more than a CSS issue. James changed the links from 'Wiki' links to HTML links and that has resolved the issue.
 * Jen to email the team photos
 * This has already been done - this photo was used in the presentation shown in Edinburgh
 * Do a new version of the timetable
 * Has been updated
 * Plan for a week off before coming back for next teaching year (September-ish), to relax before even more work 
 * Didn't discuss
 * Edinburgh itinerary to be emailed to group
 * Completed
 * Create an informal talk/presentation for the Edinburgh trip, we will run through this either on the Thursday meeting, or on an extra Friday meeting - this should contain some, but not too much technical detail, eg genes. 
 * Completed - presentation was given to participants of the iGem 2009 UK team get-together
 * Phil to be added to the mailing list
 * An administrator of the mailing list needs to do this if not done already


 * Thoughts and ideas from iGem UK get-together
 * Need to write up about ethics and social implications of project and synthetic biology
 * Awaiting e-mail from Edinburgh University regarding ideas and thoughts generated from the discussion activity
 * Need to write up a report of the Edinburgh trip
 * James has written a few paragraphs which has been posted onto the internal wiki
 * Add photos and presentation to the wiki
 * Ongoing


 * Any questions or concerns
 * Ask about MatLab
 * Ask about Sequentia tutorial
 * Ask about uploading information onto external wiki