Team:Berkeley Wetlab/Passenger: Leucine Zippers

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==Leucine Zippers==
==Leucine Zippers==
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One potential use of cell surface display is to adhere cells together selectively such that you can create a structure. The first step of such an endeavor is create a basic system of adhere 2 cells types together. One way of doing so is to use leucine zippers, a common dimeric protein motif. Leucine zippers are short peptides that form alpha helices that compliment each other. Using a GNC4 leucine zipper heterodimers KILR and EILD, we hoped to adhere cells to one another.
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One potential use of cell surface display is to adhere cells together selectively such that there is structure. However, such a feat is impossible to do in one step. In order to work up to such a goal, the first step of such an endeavor is create a basic system of adhere 2 cells types together. We propse using dimeric leucine zippers to adhere cells to one another. Leucine zippers are short peptides which form alpha helices that compliment each other. Using a GNC4 leucine zipper heterodimers KILR and EILD, we hoped to adhere cells to one another.

Revision as of 22:36, 20 October 2009

Leucine Zippers

One potential use of cell surface display is to adhere cells together selectively such that there is structure. However, such a feat is impossible to do in one step. In order to work up to such a goal, the first step of such an endeavor is create a basic system of adhere 2 cells types together. We propse using dimeric leucine zippers to adhere cells to one another. Leucine zippers are short peptides which form alpha helices that compliment each other. Using a GNC4 leucine zipper heterodimers KILR and EILD, we hoped to adhere cells to one another.