Minnesota/10 June 2009

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Latest revision as of 19:41, 29 July 2009

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Group members began to familiarize themselves with the GUI used for designing the reaction networks (naturally called designGUI). Additionally, we learned the syntax used to submit jobs to the supercomputer at the Minnesota Supercomputing Institute, the organization of the .nc files created by designGUI to store all the information of the model, and received the initial experimental data for each model:

Figure 1 - TNN Experiment

Figure 2 - TTN Experiment

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+Group members began to familiarize themselves with the GUI used for designing the reaction networks (naturally called designGUI). Additionally, we learned the syntax used to submit jobs to the supercomputer at the Minnesota Supercomputing Institute, the organization of the .nc files created by designGUI to store all the information of the model, and received the initial experimental data for each model:<br>
-Since there are several problems with the first TNN model, we are deciding to focus on them one at a time. The first thing to work on is the leakiness problem. In order to deal with this issue, we are including a reaction that allows for the binding of the RNA polymerase to the operator site even if the site is occupied by a tetR. This will allow for some expression at an aTc concentration of 0, because at this point tetR is almost always bound to the tetO operator.
+<center>
+<gallery widths=400 heights=300>
-Here is the model we are working on:
+Image:Tnnmatrix_IPTG0.jpg|Figure 1 - TNN Experiment
+Image:TTNExperiment.jpg|Figure 2 - TTN Experiment
+</gallery>
+</center>