Team:Groningen/Brainstorm/Growth Control

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Home The Team Brainstorm Our Vision Parts Modelling Notebook

Contents

Introduction

Under construction

Previous contests

Cell cycle

  • [http://parts.mit.edu/wiki/index.php/Synchronization_of_Cell_Cycles| Bangalore 2006]
  • Strasbourg 2008

Parts in the [http://partsregistry.org/Main_Page Registry of Standard Parts]:

Quorum sensing

  • [http://partsregistry.org/Part:BBa_K104001 BBa_K104001]: Sensor for small peptide Subtilin

Cell cycle

  • [http://partsregistry.org/Part:BBa_M31201 Part:BBa_M31201]
  • [http://partsregistry.org/Part:BBa_K105013 Part:BBa_K105013]
  • [http://partsregistry.org/Part:BBa_K105015 Part:BBa_K105015]
  • [http://partsregistry.org/Part:BBa_K101017 Part:BBa_K101017] a cell-cycle dependent promoter that is repressed before initiation of replication and depressed shortly after
  • [http://partsregistry.org/Part:BBa_J22051 Part:BBa_J22051] an adenylate cyclase promoter, expression is repressed during cell division
  • [http://partsregistry.org/Part:BBa_J22052 Part:BBa_J22052] an adenylate cyclase promoter, expression is repressed during cell division
  • [http://partsregistry.org/Part:BBa_J22095 Part:BBa_J22095]
  • [http://partsregistry.org/Part:BBa_J22092 Part:BBa_J22092]

Cell death

  • [http://partsregistry.org/Part:BBa_I745006 Part:BBa_I745006]
  • [http://partsregistry.org/Part:BBa_I745007 Part:BBa_I745007]
  • [http://partsregistry.org/Part:BBa_K145008 Part:BBa_K145008] LuxR Generator
  • [http://partsregistry.org/Part:BBa_K145009 Part:BBa_K145009] ccdB cell death gene under control of an activating Lux PR
  • [http://partsregistry.org/Part:BBa_K145109 Part:BBa_K145109] ccdB cell death gene under the control of a hybrid LuxPR P22 C2 promotor
  • [http://partsregistry.org/Part:BBa_K145110 Part:BBa_K145110] Complete cell death mechanism. Combination of [http://partsregistry.org/Part:BBa_K145108 Part:BBa_K145108] and [http://partsregistry.org/Part:BBa_K145109 Part:BBa_K145109]
  • [http://partsregistry.org/Part:BBa_K145151 Part:BBa_K145151] Coding region for the ccdB (control of cell death) gene
  • [http://partsregistry.org/Part:BBa_K145230 Part:BBa_K145230] A hybrid promoter controls the production of LuxR and ccdB
  • [http://partsregistry.org/Part:BBa_K145256 Part:BBa_K145256] Cell death Part 1
  • [http://partsregistry.org/Part:BBa_K145257 Part:BBa_K145257] Cell death Part 2

Related Literature

Quorum sensing

  • [http://www.ncbi.nlm.nih.gov/pubmed/15374644 Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis], Kleerebezem
In this paper, the molecular mechanism underlying regulation of nisin and subtilin production is reviewed.
  • [http://www.ncbi.nlm.nih.gov/pubmed/9675856 Induction of entry into the stationary growth phase in Pseudomonas aeruginosa by N-acylhomoserine lactone], You et al.
Addition of N-acylhomoserine lactone in the exponential growth phase, regardless of cell density, induces a repression of cell growth of P. aeruginosa
  • [http://www.ncbi.nlm.nih.gov/pubmed/12032343 Induction of natural competence in Streptococcus pneumoniae triggers lysis and DNA release from a subfraction of the cell population], Steinmoen et al.
In this study Competence stimulating peptide is shown to initiates release of DNA from a subfraction of the bacterial population, probably by cell lysis.