Team:KULeuven/Modeling/Vanillin Production

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Contents

Vanillin Production

overview

Vanillin production overview starting from Tyrosine.

The vanillin synthesis consists of a five step process starting from tyrosine. Both the transcription of the Sam 8 and COMT enzyme are locked to prevent vanillin synthesis without the presence of RIBOKEY. E. coli controls its own tyrosine production. However,should this be insufficient, we can always add extra tyrosine. The production process will be tested in two steps. First, from tyrosine to ferrulic acid; then from ferrulic acid to vanillin.

Biologie vanillin synthesis.png
Biologie vanillin synthesis short.png
Biologie vanillin synthesis shortII.png

Models

Vanillin production.png

Simulation

The following figure shows that the steady state level of vanillin concentration is (non linearly) regulated by the amount of mRNA input key.

Vanillin.png