Team:Newcastle/Modelling

From 2009.igem.org

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= Computational Modelling =
= Computational Modelling =
[[Image:Team Newcastle iGem 2009 08-07-09 no 7.JPG|300px|center]]
[[Image:Team Newcastle iGem 2009 08-07-09 no 7.JPG|300px|center]]
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The modelling in our 2009 iGEM project, BacMan, can be split into a number of sections - the [[Team:Newcastle/Modelling/Stochastic|Stochastic Switch]], [[Team:Newcastle/Modelling/Degradation|Degradation system]], [[Team:Newcastle/Modelling/MetalIntake|Metal Intake]], [[Team:Newcastle/SporulationTuning#Modelling|Sporulation Tuning]] and [[Team:Newcastle/Modelling/Population|Population Simulation]]. We are particularly proud of our Population Simulation Model as it combines distributed computing, agent based and cellular models.
For computational modelling, we are using a number of technologies, including [[Team:Newcastle/Java|Java]], [[Team:Newcastle/Matlab|Matlab]], [[Team:Newcastle/Amazon EC2|Amazon EC2]], [[Team:Newcastle/Microbase|Microbase]], [[Team:Newcastle/SBML|SBML]] and [[Team:Newcastle/CellML|CellML]].
For computational modelling, we are using a number of technologies, including [[Team:Newcastle/Java|Java]], [[Team:Newcastle/Matlab|Matlab]], [[Team:Newcastle/Amazon EC2|Amazon EC2]], [[Team:Newcastle/Microbase|Microbase]], [[Team:Newcastle/SBML|SBML]] and [[Team:Newcastle/CellML|CellML]].
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=== Stochastic Switch ===
=== Stochastic Switch ===
: '' See [[Team:Newcastle/Modelling/Stochastic|Stochastic Switch Model]]''
: '' See [[Team:Newcastle/Modelling/Stochastic|Stochastic Switch Model]]''
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We are modelling our stochastic switch.
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We have modelled our stochastic switch.
We also designed an inducible protein degradation system for our switch.
We also designed an inducible protein degradation system for our switch.
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<!--: '' See [[Team:Newcastle/Modelling/Tuning]]''-->
<!--: '' See [[Team:Newcastle/Modelling/Tuning]]''-->
: '' See [[Team:Newcastle/SporulationTuning#Modelling|Sporulation Tuning Model]]''
: '' See [[Team:Newcastle/SporulationTuning#Modelling|Sporulation Tuning Model]]''
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Some of our models look at tuning sporulation, so that we can influence the decision of the cells.
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Another of our models looks at tuning sporulation.
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=== Metal Intake ===
=== Metal Intake ===
: '' See [[Team:Newcastle/Modelling/MetalIntake|Metal Intake Model]]''
: '' See [[Team:Newcastle/Modelling/MetalIntake|Metal Intake Model]]''
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Another of our models looks at metal intake.
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Another of our models looks at metal intake. Specifically this looks at Cadmium transport throughout our bacteria.
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Revision as of 00:14, 21 October 2009


Computational Modelling

Team Newcastle iGem 2009 08-07-09 no 7.JPG

The modelling in our 2009 iGEM project, BacMan, can be split into a number of sections - the Stochastic Switch, Degradation system, Metal Intake, Sporulation Tuning and Population Simulation. We are particularly proud of our Population Simulation Model as it combines distributed computing, agent based and cellular models.

For computational modelling, we are using a number of technologies, including Java, Matlab, Amazon EC2, Microbase, SBML and CellML.

Sub-projects

Stochastic Switch

See Stochastic Switch Model

We have modelled our stochastic switch.

We also designed an inducible protein degradation system for our switch.

See Degradation Model

Population Modelling

See Population Simulation

One of the models which we are producing is one concerning the population numbers of our bacteria. It looks at how our additions to the DNA may affect the growth of the bacterial population.

Sporulation Tuning

See Sporulation Tuning Model

Some of our models look at tuning sporulation, so that we can influence the decision of the cells.

Metal Intake

See Metal Intake Model

Another of our models looks at metal intake. Specifically this looks at Cadmium transport throughout our bacteria.




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