Team:Valencia

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<title>iGEM 2009 Valencia</title>
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== '''iGEM Valencia Lighting Cell Display (iLCD)''' ==
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<span style="color:black; align:justify; font-size:11pt; font-family: Verdana">The <b>iGEM Valencia Lighting Cell Display</b> (<b>iLCD</b>) is our project for the present iGEM competition. We plan to '''control cell behaviour whith an electrical stimulous'''. Our intention is to advance in the development of '''BioElectronics''' allowing enabling bidirectional communication of monocellular organisms and electronic components.
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<span style="color:black; align:justify; font-size:11pt; font-family: Verdana">To demostrate that this is possible we try to make <b>a “bio-screen” of voltage-activated cells</b>, where every “cellular pixel” produces light. Using electrical signals instead of chemical stimulation, as in the Coliroid project (Levskaya et al, <i>Synthetic biology: Engineering Escherichia coli to see light</i>. <b>Nature</b> 438, 441-442), <b>we will be able to see animated pictures!</b>
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<span style="color:black; align:justify; font-size:11pt; font-family: Verdana"><b>Engineered yeasts that are able to sense and respond to electrical signals will be used</b>. We will design an electronic device which allows the cooperative work of all the cells in such a way that they will be able to <b>reproduce an image in movement, building up a "bio-screen" for the first time in history</b>.
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<span style="color:black; align:justify; font-size:11pt; font-family: Verdana">We are also going to reflect on the perception that different groups of people, from a variety of educational levels and professional areas, have of Synthetic Biology. For this reason, <b>we have made a survey that has already finished</b> that we are sure will be of interest.
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<p> A “bio-screen” of voltage-activated cells, where every “cellular pixel” produces light. Using electrical signals instead of chemical stimulation, we are be able to see animated pictures!</p>
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<h2><b>Project</b> description</h2>
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<img src="https://static.igem.org/mediawiki/2009/6/6a/Valencia_Nino2.gif" width="112" height="92" alt="Pic 1" class="left" />
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<p>Engineered yeasts able to sense and respond to electrical signals are build (what we call <b>LEC</b>). Thanks to a homemade device These <b>LEC</b>s  work cooperatively  in such a way that they are able to reproduce images in movement, building up a "bio-screen" for the first time in history. </p>
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"As Lumières revolutioned the photography world, Valencia Team revolutions the bacterial photography world"</i>
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<li> <a href="https://2009.igem.org/Team:Valencia/WetLab/YeastTeam">LEC construction</a>. </li>
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<li> <a href="https://2009.igem.org/Team:Valencia/Modelling">LEC characterization</a>. </li>
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<li> <a href="https://2009.igem.org/Team:Valencia/Hardware">LEC Integration in the first iLCD.</a> </li>
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<p class="more">
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<span style="color:black; align:justify; font-size:11pt; font-family: Verdana"><b>Is important to note that iLCD will be a major advance in Synthetic Biology, opening the field of ''BioElectronics'', integrating electrical signals with cell behaviours</b>. Furthermore, this will reduce the response time of the cells to the activation signal by up to two orders of magnitude, as well as foster the combination of Electronics and Biology.
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<span style="color:black; align:justify; font-size:11pt; font-family: Verdana">In resume, we have two objectives: control cell behaviour whith electrical stimulous and reduce the time of response respect a previous projects.
 
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<h2><b>Human Practices</b> Report</h2>
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<p>Sins, Ethics and Biology, a Comprehensive Approach is more than a review on Human Practices and Synthetic Biology it emcompasses:</p>
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<p> Classical review revising more than <b>50 scientific reports</b> on Human Practices.</p>
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<p> The first <b>comparative analysis</b> of previous iGEM HP projects.</p>
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<p><b>Interviews</b> with well known experts.</p>
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<p>The <b>largest survey</b> on ethics and synthetic biology ever made.</p>
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<h2><b>Valencia </b> Team  </h2>
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<p>Integrated by students from the two main Valencia Universities (<a href="http://www.upv.es">UPV</a> and <a href="http://www.uv.es">UV</a>).</p>
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<p>Emiment <b>multidisciplinary</b> group:</p>
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<p>4 Biologist, 3 Mechanical Engineers and 2 Biotech</p>
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With a great repercusion in the <a href="https://2009.igem.org/Team:Valencia/News">national media</a>!
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<h2><b>Acknowledgements</b></h2>
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<img src="https://static.igem.org/mediawiki/2009/3/30/Valencia_Solidarite.jpg" width="86" height="77" alt="Pic 4" class="left" />
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<p>This work has not been possible without the help of several Institutions and Research groups.</p>
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<p>From Valencia Team, we would like to thank to all that people that allow us to pass this summer working on this mind-blowing project</p>
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<p>To see all of them... </p>
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<p>&copy; iGEM Valencia 2009</p>
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Revision as of 23:22, 20 October 2009

iGEM 2009 Valencia

Project description

Pic 1

Engineered yeasts able to sense and respond to electrical signals are build (what we call LEC). Thanks to a homemade device These LECs work cooperatively in such a way that they are able to reproduce images in movement, building up a "bio-screen" for the first time in history.


"As Lumières revolutioned the photography world, Valencia Team revolutions the bacterial photography world"

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Human Practices Report

Pic 2

Sins, Ethics and Biology, a Comprehensive Approach is more than a review on Human Practices and Synthetic Biology it emcompasses:

Classical review revising more than 50 scientific reports on Human Practices.

The first comparative analysis of previous iGEM HP projects.

Interviews with well known experts.

The largest survey on ethics and synthetic biology ever made.

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