Team:Valencia/Simulations

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(Simulations)
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Taking into account all the factors listed in [https://2009.igem.org/Team:Valencia/OurModel '''Our Model'''] (Calcium current through VDCCs, Calcium Buffering and Calcium pumps), the result of simulating free intracellular calcium concentration after the electrical stimulation in neurons is the following:  
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Before simulating how intracellular calcium concentration changes in time, we have approximated the '''excitatory post-synaptic potential''' (our "input" function in neurons) as follows:  
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[[Image:Voltage_neurons.jpg|480px|center]]
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Then, taking into account all the factors listed in [https://2009.igem.org/Team:Valencia/OurModel '''Our Model'''] (Calcium current through VDCCs, Calcium Buffering and Calcium pumps), the result of simulating '''free intracellular calcium concentration''' after the electrical stimulation in '''neurons''' is this:
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[[Image:Voltage_neurons.jpg|480px|center]]
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Revision as of 18:12, 13 September 2009


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Simulations

Before simulating how intracellular calcium concentration changes in time, we have approximated the excitatory post-synaptic potential (our "input" function in neurons) as follows:

Voltage neurons.jpg

Then, taking into account all the factors listed in Our Model (Calcium current through VDCCs, Calcium Buffering and Calcium pumps), the result of simulating free intracellular calcium concentration after the electrical stimulation in neurons is this:


Calcium neurons.jpg