Team:UC Davis

From 2009.igem.org

(Difference between revisions)

Latest revision as of 18:07, 21 October 2009

Homepage_UCdavis

            It is estimated that about one in every 133 Americans suffer from an autoimmune disorder called Celiac Disease (14, 11). Celiac Disease is a condition in which the small intestines of an affected individual cannot properly digest gliadin, a protein present in gluten. When consumed, gliadin induces immune system responses, the side-effects of which are, but not limited to: abdominal pain, chronic diarrhea, and vomiting (14). Currently, the only accepted treatment for this disorder is adhering to a gluten-free diet (14, 12). This can be very difficult as great varieties of food contain gluten. This inspired us to imagine an alternative treatment based on a probiotic organism that can survive and take residence in the stomach, where it would secrete an enzyme that degrades gliadin.
           Then the design elements of this organism should satisfy at least two main criteria. First, it should be able to survive only in the stomach; second, it should secrete an enzyme that degrades gliadin. We envision that these parts would not only be useful for our project, but also to other future projects.
       We decided to focus our summer project on building the first of the two key elements required for our system:
                1. Produce an inducible secretion system
                2. Construct a biological pH sensor limiting this secretion system to the stomach

UC Davis iGEM team is sponsored by:

We want to thank Marc Facciotti for his helpful advice.
Special thanks to Suzy Fenton,Wayne Fenton, Jeanne Joe-Fenton and Wayne Fenton Jr.
Also we thank Charles H. Halsted for reviewing our material regarding celiac disease.

@@ Line 1: / Line 1: @@
 <html>
 <head>
-<meta http-equiv="Content-Type" content="text/html;">
+<meta content="text/html;charset=ISO-8859-1" http-equiv="Content-Type">
-	<title>UC DAVIS</title>
+<title>Homepage_UCdavis</title>
-<style>
-TD{
-   color:black;
-   font-size: 11;
-   font-family: Verdana;
-}
-.bot{
-	text-decoration: none;
-	font-size: 10;
-   font-family: verdana,Arial;
-   font-weight:bold;
-   color:black;
-}
-.copy{
-	font-size: 10;
-   font-family: verdana,Arial;
-    color:black;
-}
-</style>
 </head>
+<body style="background-color: rgb(255, 255, 255); color: rgb(0, 0, 0);"
-<body topmargin="0" rightmargin="0" marginwidth="0" marginheight="0" leftmargin="0" bottommargin="0">
+alink="#ee0000" link="#0000ee" vlink="#551a8b">
-<table width="100%" cellspacing="0" cellpadding="0" border="0"  height="100%">
+<div style="text-align: center;"><span
-<tr>
+style="color: rgb(255, 255, 153);">&nbsp;
-<td valign="top" width="900" height="100%">
+</span><b style="color: rgb(255, 255, 153);"><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b><span
-<table width="780" border="0" cellpadding="0" cellspacing="0" height="100%">
+style="color: rgb(255, 255, 153);"><img src="" alt=""
-    <tr>
+style="width: 151px; height: 161px;"></span><b
-      <td valign="top" width="780" colspan="2"><table width="780" cellpadding="0" cellspacing="0" border="0">
+style="color: rgb(255, 255, 153);"><span
-	                                               <tr><td width="283"><img src="images/club.jpg" border="0" width="283" height="76" alt=""></td>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b><b
-	                                                    <td height="76" valign="middle" width="470" align="right"><table style="border-collapse: collapse; border-color: silver;" border="1" width="200">
+style="color: rgb(255, 255, 153);"><span
-													  		     <tr>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b><a
+href="https://2009.igem.org/Team:UC_Davis/About_Us"><b
-                                                                                               </td>
+style="color: rgb(255, 255, 153);"><span
-																 </tr></form></table></td>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b></a><b
+style="color: rgb(255, 255, 153);"><span
-													<td width="17">&nbsp;</td>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b><a
-													</tr>
+href="https://2009.igem.org/Team:UC_Davis/About_Us"><b
-										+114	</table></td>
+style="color: rgb(255, 255, 153);"><span
-    </tr>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b></a><b
-    <tr>
+style="color: rgb(255, 255, 153);"><span
-      <td valign="top" colspan="2"><img src="https://static.igem.org/mediawiki/2009/0/0f/UC_Davis_M7.jpg" border="0" width="82" height="32" alt=""><img src="https://static.igem.org/mediawiki/2009/c/c9/UC_Davis_m1.jpg" border="0" width="108" height="32" alt=""><img src="https://static.igem.org/mediawiki/2009/d/df/UC_Davis_M2.jpg" border="0" width="108" height="32" alt=""><img src="https://static.igem.org/mediawiki/2009/6/67/UC_Davis_M3.jpg" border="0" width="108" height="32" alt=""><img src="https://static.igem.org/mediawiki/2009/b/b1/UC_Davis_M4.jpg" border="0" width="108" height="32" alt=""><img src="https://static.igem.org/mediawiki/2009/a/a1/UC_Davis_M5.jpg" border="0" width="111" height="32" alt=""><img src="https://static.igem.org/mediawiki/2009/b/b4/UC_Davis_M6.jpg" border="0" width="155" height="32" </td>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b><b
-    </tr>
+style="color: rgb(255, 255, 153);"><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><big><big><big><big>&nbsp;
-    <tr>
+</big></big></big></big></span></b><b style="color: rgb(255, 255, 153);"><span
-      <td valign="top" width="622"  height="100%" bgcolor="#CCCCCC" ><img src="https://static.igem.org/mediawiki/2009/c/ce/UC_Davis_Banner.png" border="0" width="622" height="98" alt=""><br>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><big><big><big><big><a
-        	  <table width="622" border="0" cellpadding="0" cellspacing="0" bgcolor="#CCCCCC"   >
+href="https://2009.igem.org/Team:UC_Davis/About_Us"><img alt=""
-                   <tr>
+src="https://static.igem.org/mediawiki/2009/d/d1/UCDAVIS_PIC4.png"
-                     <td valign="top"  width="417" ><img src="images/text.jpg" border="0" width="417" height="44" alt="">
+style="border: 0px solid ; width: 92px; height: 46px;"></a> </big></big></big></big></span></b><b
-					  <table width="417" border="0" cellpadding="0" cellspacing="0">
+style="color: rgb(255, 255, 153);"><span
-                         <tr>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><big><big><big><big><a
-                           <td valign="top">&nbsp;&nbsp;&nbsp;</td>
+href="https://2009.igem.org/Team:UC_Davis/Project"><img alt=""
-                           <td valign="top">
+src="https://static.igem.org/mediawiki/2009/b/b9/UCDAVIS_PIC8.png"
+style="border: 0px solid ; width: 92px; height: 46px;"></a> </big></big></big></big></span></b><b
-						             NOTE TO SELF! ADD TEXT HERE. <br><br>
+style="color: rgb(255, 255, 153);"><span
-							 NOTE TO SELF! ADD TEXT HERE.  <br><br>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><big><big><big><big><a
- 							 NOTE TO SELF! ADD TEXT HERE.  <br><br>
+href="https://2009.igem.org/Team:UC_Davis/Notebook"><img alt=""
+src="https://static.igem.org/mediawiki/2009/2/2f/UCDAVIS_PIC5.png"
-						    </td>
+style="border: 0px solid ; width: 92px; height: 46px;"></a> </big></big></big></big></span></b><b
+style="color: rgb(255, 255, 153);"><span
-                           <td valign="top">&nbsp;&nbsp;&nbsp;</td>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b><b
-                         </tr>
+style="color: rgb(255, 255, 153);"><span
-                       </table></td>
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><big><big><big><big><a
-                     <td valign="top" width="9" background="images/v_l_bg.jpg"><img src="images/v_line.jpg" border="0" width="9" height="44" alt=""></td>
+href="https://2009.igem.org/Team:UC_Davis/Parts"><img alt=""
-                     <td valign="top"><img src="images/news.jpg" border="0" width="196" height="44"
+src="https://static.igem.org/mediawiki/2009/a/a6/UCDAVIS_PIC6.png"
-					 alt=""><table width="196" border="0" cellpadding="0" cellspacing="0">
+style="border: 0px solid ; width: 92px; height: 46px;"></a>&nbsp;<a
-                              <tr>
+href="https://2009.igem.org/Team:UC_Davis/Contacts_References"><img
-                                <td valign="top">&nbsp;&nbsp;&nbsp;</td>
+alt="" src="https://static.igem.org/mediawiki/2009/1/1d/UCDAVIS_PIC7.png"
-                                <td valign="top" style="font-family:arial;" >
+style="border: 0px solid ; width: 92px; height: 46px;"></a></big></big></big></big></span></b><b
-								    <b>12&nbsp;Feb&nbsp;2002&nbsp;::&nbsp;</b> UPDATE 1<br>TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT <br><br>
+style="color: rgb(0, 0, 0);"><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><big><big><big><big><small>
-								    <b>12&nbsp;Feb&nbsp;2002&nbsp;::&nbsp;</b> UPDATE 2<br>TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT <br><br>
+<img style="width: 191px; height: 147px;" alt="" src=""><br>
-								    <b>12&nbsp;Feb&nbsp;2002&nbsp;::&nbsp;</b> UPDATE 3<br>TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT TEXT <br><br>
+</small></big></big></big></big></span></b></div>
-								<div align="right"><a href="" style="color: black;text-decoration:none;"><b>More Press&gt;&gt;</a>&nbsp;&nbsp;&nbsp;</b></div><br><br>
+<hr style="width: 100%; height: 2px;"><b style="color: rgb(0, 0, 0);"><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b><big><span
-								</td>
+style="color: rgb(0, 0, 0);"></span></big><b
-                                <td valign="top">&nbsp;&nbsp;&nbsp;</td>
+style="color: rgb(0, 0, 0);"><span
-                              </tr>
+style="font-size: 13pt; line-height: 115%; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><span
-      	                   </table></td>
+style="font-family: Symbol;"></span><span
-                   </tr>
+style="font-family: Arial Narrow; font-weight: bold;"></span></span></b><span
-				   <tr><td width="622" height="19" background="images/h_l_bg.jpg" colspan="3">&nbsp;</td></tr>
+style="color: rgb(0, 0, 0); font-family: Arial Narrow; font-weight: bold;"><span
-               </table>
+style="font-size: 13pt; line-height: 115%;"></span></span>
-	  </td>
+<p class="MsoNormal"
-      <td background="https://static.igem.org/mediawiki/2009/4/40/UC_Davis_Bg2.jpg" valign="top" width="158" >&nbsp;</td>
+style="margin-bottom: 0.0001pt; line-height: normal;"><b><span
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;; color: black;">&nbsp;&nbsp;&nbsp;
-    </tr>
+&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;<big> </big></span></b><span
-    <tr>
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;; color: black; font-weight: bold;"><big>&nbsp;
-      <td valign="top" colspan="2" align="center" height="20"><br><br>
+</big><big>It
-	  <a class="bot" href="">MENU</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+is estimated that about one in
-	  <a class="bot" href="">MENU</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+every 133 Americans suffer from an autoimmune disorder called Celiac
-	  <a class="bot" href="">MENU</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+Disease
-	  <a class="bot" href="">MENU</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+(14, 11). Celiac Disease is a condition in which the small intestines of
+an
-	  <a class="bot" href="">MENU</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+affected individual cannot properly digest gliadin, a protein present
-	  <a class="bot" href="">MENU</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+in gluten.
-	  <a class="bot" href="">MENU</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+When
-	  <a class="bot" href="">MENU</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+consumed, gliadin induces immune system responses, the
-	  <a class="bot" href="">MENU</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+side-effects of which are,
+but not limited to: abdominal pain, chronic diarrhea, and vomiting (14).
-	  <br>
+Currently, the only accepted treatment for this disorder is adhering to
+a
+gluten-free diet (14, 12). This can be very difficult as great
+varieties of
-    </tr>
+food contain gluten. This inspired us to imagine an alternative
-</table>
+treatment based on a probiotic organism
+that can
+survive and take residence in the stomach, where it would secrete an
-</td>
+enzyme that
-<td width="100%" background="images/bg.gif">&nbsp;</td>
+degrades gliadin.</big></span><big style="font-weight: bold;"><span
-</tr>
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><br>
-</table>
+&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp; &nbsp;&nbsp; Then the design
+elements of this organism should satisfy at least two main
+criteria.
+First, it
+should be able to survive only in the stomach; second, it should secrete an
+enzyme
+that degrades gliadin<i>.</i> We envision that these parts would
+not
+only be useful for our project, but also to other future projects.</span><span
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><o:p></o:p></span><br>
+</big><span style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><big
+style="font-weight: bold;">&nbsp;&nbsp;&nbsp;
+&nbsp; &nbsp;
+&nbsp;&nbsp; We decided to focus our summer project on building the
+first of the two key elements
+required for
+our system:<o:p></o:p><br>
+&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;
+&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp; 1. <a
+href="https://2009.igem.org/Team:UC_Davis/secretion">Produce an
+inducible secretion
+system</a><br>
+</big>
+<big style="font-weight: bold;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+. <a href="https://2009.igem.org/Team:UC_Davis/ph_sensor1">Construct a
+biological pH sensor limiting this secretion system to
+the
+stomach</a></big></span><a
+href="https://2009.igem.org/Team:UC_Davis/ph_sensor1"><span
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><span
+style="text-decoration: underline;"></span></span></a><span
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><big
+style="font-weight: bold;"><br>
+</big></span></p>
+<p class="MsoNormal"
+style="margin-bottom: 0.0001pt; line-height: normal;"><span
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span><a
+href="https://2009.igem.org/Team:UC_Davis/ph_sensor1"><b
+style="color: rgb(0, 0, 0);"><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b></a><span
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;
+&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;
+&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;
+&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;
+&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;
+&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+&nbsp;</span><a href="https://2009.igem.org/Team:UC_Davis/ph_sensor1"><span
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"><span
+style="text-decoration: underline;"></span></span></a><a
+href="https://2009.igem.org/Team:UC_Davis/Project_Summary"><img alt=""
+src="https://static.igem.org/mediawiki/2009/a/ac/UCDAVIS_summary.png"
+style="border: 0px solid ; width: 63px; height: 50px;"></a><span
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+<span style="text-decoration: underline;"><br>
+</span> </span><a href="https://2009.igem.org/Team:UC_Davis/ph_sensor1"><b
+style="color: rgb(0, 0, 0);"><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b></a><span
+style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span><b
+style="color: rgb(0, 0, 0);"><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b></p>
+<hr style="width: 100%; height: 2px;">
+<p class="MsoNormal"
+style="margin-bottom: 0.0001pt; line-height: normal; color: rgb(0, 0, 0); text-align: center; background-color: rgb(255, 255, 255);"><b><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b><b><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b><b><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b><b><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;"></span></b></p>
+<ul style="background-color: rgb(255, 255, 255); color: rgb(0, 0, 0);">
+</ul>
+<div style="text-align: center;"><big> </big></div>
+<div style="text-align: center;">
+<div style="text-align: left;">
+<div style="text-align: center;"><big><span style="font-weight: bold;"><big>&nbsp;&nbsp;
+&nbsp;&nbsp;<small>
+UC
+Davis iGEM team is sponsored by:</small></big></span></big><br>
+<big><span style="font-weight: bold;"></span></big></div>
+<div style="text-align: center;">&nbsp;&nbsp; &nbsp;&nbsp; <img
+src="https://static.igem.org/mediawiki/2009/8/88/UCDAVIS_Biomedical_engineering.jpg"
+alt="" style="width: 83px; height: 109px;"><img
+style="width: 105px; height: 109px;" alt=""
+src="https://static.igem.org/mediawiki/2009/4/43/UCDAVIS_college_of_engineering.png"><img
+style="width: 135px; height: 99px;" alt=""
+src="https://static.igem.org/mediawiki/2009/8/8e/UCDAVIS_Accutek1.jpg"><img
+style="width: 121px; height: 109px;" alt=""
+src="https://static.igem.org/mediawiki/2009/6/6b/UCDAVIS_mrgen.gif"><img
+style="width: 182px; height: 108px;" alt=""
+src="https://static.igem.org/mediawiki/2009/c/c6/UCDAVIS_genome_center.jpg"><br>
+<font size="-1">We want to thank <span style="font-weight: bold;">Marc</span>
+<span style="font-weight: bold;">Facciotti</span> for his helpful
+advice.<br>
+Special thanks to <span style="font-weight: bold;">Suzy
+Fenton</span>,<span style="font-weight: bold;">Wayne Fenton, Jeanne
+Joe-Fenton </span>and<span style="font-weight: bold;"> Wayne Fenton Jr.</span>
+<br>
+Also we thank <span style="font-size: 10pt; line-height: 115%;"><b>Charles
+H. <span class="il">Halsted </span></b><span class="il">for reviewing
+our material regarding celiac disease.</span></span></font><br>
+<br>
+</div>
+</div>
+</div>
+<ul style="background-color: rgb(255, 255, 255); color: rgb(0, 0, 0);">
+<span style="font-weight: bold;"></span>
+</ul>
+<p class="MsoNormal"
+style="margin-bottom: 0.0001pt; line-height: normal; color: rgb(0, 0, 0); text-align: left; background-color: rgb(255, 255, 255);"><b><span
+style="font-size: 13.5pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
+</span></b></p>
+<span style="color: rgb(0, 0, 0);"></span>
 </body>
 </html>