From 2009.igem.org
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| - | ==To find==
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| - | PDB files of LOV domain, TrpR repressor => http://www.rcsb.org/pdb/home/home.do
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| - | ==To do==
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| - | <br>- Set up day of starting modeling, do a planning for modeling => see with Matteo Dal Peraro
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| - | <br>- Model allosteric interactions between LOVTAP & TrpR
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| - | <br>- Do a mutational assay to change specificity of LOVTAP:
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| - | <br> Direct mutational assay: Insert mutation in specific sites thanks to the known structure of LOVTAP (already modeled on computer)
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| - | <br> Indirect mutational assay: Random mutations, then selection of the "right" protein according to a set of selected conditions
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| - | <br>- Model the fusion of LOV domain with other transcription factors
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| - |
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| - | ==To envisage ==
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| - | <br>- Molecular mutationnal assay
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| - | ----
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| - | {| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
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| - | !align="center"|[[Team:EPF-Lausanne|Home]]
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| - | !align="center"|[[Team:EPF-Lausanne/Team|The Team]]
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| - | !align="center"|[[Team:EPF-Lausanne/Project|The Project]]
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| - | !align="center"|[[Team:EPF-Lausanne/Parts|Parts Submitted to the Registry]]
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| - | !align="center"|[[Team:EPF-Lausanne/Modeling|Modeling]]
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| - | !align="center"|[[Team:EPF-Lausanne/Notebook|Notebook]]
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| - | !align="center"|[[Team:EPF-Lausanne/Lectures|Lectures]]
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| - | !align="center"|[[Team:EPF-Lausanne/Team Management|Team Management]]
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| - | |}
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Latest revision as of 20:10, 10 July 2009
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