Latest revision as of 01:42, 22 October 2009

Micro-Motor - Overview

Generating mechanical power to drive microdevices has great implications in future energy utilization as well as medical science. Fortunately, nature has provided us with numerous brilliant examples of nano-scale molecular machines. Some functional nanodevices derived from living organisms, such as motor proteins, can efficiently convert chemical energy into mechanical work.

Using microorganisms to propel micromotors has a number of unique advantages over conventional energy utilization process. This includes efficient conversion of chemical energy into mechanical work and the potential of procedural control. The development of an appropriate interface between microorganisms and synthetic devices should enable us to realize useful hybrid micro-machines.

In our bactomotor project, the micromotor is one of the most important parts. It provides a surface for the microorganisms to attach, so as to concentrate propelling forces generated by the microorganisms. In order to achieve this design, the well-studied biotin-strepatavidin interaction was applied to bind the bacteria to the motor.

The micro-motor should have the following characteristics:

It should be symmetrical and small enough due to the size of microorganisms.
The motor binding the E. coli or Salmonella need an asymmetrical surface modification, with only one side of the surface coated by biotin, so that the total effect to the motor by the microorganisms will be a unidirection moment.

Besides, there are also several requirements for the material of the motor. For example, it needs to be rigid and easy for chemical modifications to coat biotin.

After trying many possible designs, we report two versions of motors. Ones is using Immobilon-P transfer membrane by mechanical cutting to small size, and the other one was photolithography photoetching method to make a silicon based motor.

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 =Micro-Motor - Overview=
-The potential to generate mechanical power to drive microdevices has a great significance in future energy exploitation as well as medical science. Fortunately, nature has provides numerous examples of nanometer-scale molecular machines. Some functional nanodevices derived from living systems, like motor proteins, can efficiently convert chemical energy into mechanical work.
+Generating mechanical power to drive microdevices has great implications in future energy utilization as well as medical science. Fortunately, nature has provided us with numerous brilliant examples of nano-scale molecular machines. Some functional nanodevices derived from living organisms, such as motor proteins, can efficiently convert chemical energy into mechanical work.
-Using life-form power to propel micromotors has a number of unique advantages over other energy generating process, including efficient conversion of chemical energy into mechanical work and the potential for procedure control. The development of an appropriate interface between such biological materials and synthetic devices should enable us to realize useful hybrid micromachines.
+Using microorganisms to propel micromotors has a number of unique advantages over conventional energy utilization process. This includes efficient conversion of chemical energy into mechanical work and the potential of procedural control. The development of an appropriate interface between microorganisms and synthetic devices should enable us to realize useful hybrid micro-machines.
-In this project, we described some micromotors driven by bacteria. The motor is one of the most important parts of the bactomotor project. It provides a surface on which the E. coli cells can bind to and the swimming motion of them can be used to propel it. In order to achieve this design, the well-studied biotin-strepatavidin interaction was applied to bind the bacteria to the motor.
+In our bactomotor project, the micromotor is one of the most important parts. It provides a surface for the microorganisms to attach, so as to concentrate propelling forces generated by the microorganisms. In order to achieve this design, the well-studied  [[Team:HKU-HKBU/Protocols#Membrane_Biotinylation | biotin-strepatavidin]]  interaction was applied to bind the bacteria to the motor.
-The motor we need should have the following two main characteristics:
+The micro-motor should have the following characteristics:
-# It should be symmetrical and small enough to match the size of bacteria, saying ~ 50μm.
+# It should be symmetrical and small enough due to the size of microorganisms.
-# It is feasible that only one side of the motor has biotin binding on it, which means that bacteria can push the motor to rotate in either clockwise or counterclockwise.
+# The motor binding the ''E. coli'' or ''Salmonella'' need an asymmetrical surface modification, with only one side of the surface coated by biotin, so that the total effect to the motor by the microorganisms will be a unidirection moment.
-Besides, it needs to be rigid and can undergo chemical modifications through which biotin can be coated on its surface.
+Besides, there are also several requirements for the material of the motor. For example, it needs to be rigid and easy for chemical modifications to coat biotin.
-With the above considerations taken into, we have designed two versions of motor, by using either Immobilon-P transfer membrane or the inorganic elemental silicon.
+After trying many possible designs, we report two versions of motors. Ones is using [[Team:HKU-HKBU/Motor_Membrane_Version | Immobilon-P transfer membrane]] by mechanical cutting to small size, and the other one was [[Team:HKU-HKBU/Motor_Silicon_Version | photolithography photoetching method]] to make a silicon based motor.
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Team:HKU-HKBU/Motor Overview

From 2009.igem.org

Latest revision as of 01:42, 22 October 2009

Micro-Motor - Overview