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| | <h1>Heavy metal scavengers<!-- with a vertical gas drive--></h1> | | <h1>Heavy metal scavengers<!-- with a vertical gas drive--></h1> |
| | Human health and the environment are endangered by heavy metal pollution in water and sediment. To battle this problem, a '''purification strategy''', in which arsenic, zinc and copper are removed from water and sediment, was developed. This strategy encompasses a biological device in which <i>E. coli</i> bacteria accumulate metal ions from solutions, after which they '''produce gas vesicles''' and '''start floating'''. This biological device consists of two integrated systems: one for metal uptake and storage, the other for metal induced buoyancy. The uptake and storage system consists of a [[Team:Groningen/Project/Transport|metal transporter]] and [[Team:Groningen/Project/Accumulation|metal binding proteins]] (to reduce toxicity and increase accumulation). The buoyancy system is made up of a [[Team:Groningen/Project/Promoters|metal induced promotor]] in front of a [[Team:Groningen/Project/Vesicle|gas vesicle gene cluster]]. The combination of both systems will enable the efficient cleaning of polluted water and sediment in a biological manner. | | Human health and the environment are endangered by heavy metal pollution in water and sediment. To battle this problem, a '''purification strategy''', in which arsenic, zinc and copper are removed from water and sediment, was developed. This strategy encompasses a biological device in which <i>E. coli</i> bacteria accumulate metal ions from solutions, after which they '''produce gas vesicles''' and '''start floating'''. This biological device consists of two integrated systems: one for metal uptake and storage, the other for metal induced buoyancy. The uptake and storage system consists of a [[Team:Groningen/Project/Transport|metal transporter]] and [[Team:Groningen/Project/Accumulation|metal binding proteins]] (to reduce toxicity and increase accumulation). The buoyancy system is made up of a [[Team:Groningen/Project/Promoters|metal induced promotor]] in front of a [[Team:Groningen/Project/Vesicle|gas vesicle gene cluster]]. The combination of both systems will enable the efficient cleaning of polluted water and sediment in a biological manner. |
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| - | <li id="arsenic"></html>It all starts with [[Team:Groningen/Application|arsenic]] in solution.<html></li>
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| - | <li id="transport"></html>[[Team:Groningen/Project/Transport|Metal transport]]<html></li>
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| - | <li id="accumulation"></html>[[Team:Groningen/Project/Accumulation|Metal accumulation]]<html></li>
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| - | <li id="gas"></html>[[Team:Groningen/Project/Vesicle|Gas Vesicle]]<html></li>
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| - | <li id="promoter"></html>[[Team:Groningen/Project/Promoters|Metal sensitive promoters]]<html></li>
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| - | |{{linkedImage|Model_front.png|Modelling}} | + | |{{linkedImage|Model_front.png|Team:Groningen/Modelling}} |
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| - | <b><u><h1>Where to meet us</h1></u></b>
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| - | *{{todo}} December 11<sup>th</sup> 2009: Meeting @ [http://www.dsm.com/en_US/html/home/dsm_home.cgi DSM] - [http://maps.google.nl/maps?oe=utf-8&rls=org.mozilla:nl:official&client=firefox-a&um=1&ie=UTF-8&q=delft+DSM&fb=1&gl=nl&hq=DSM&hnear=delft&cid=0,0,8723601113946313921&ei=B_jSSrqHIcTz-QbZsNT7Ag&sa=X&oi=local_result&ct=image&resnum=1&ved=0CAoQnwIwAA Delft]
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| - | *{{todo}} November 23<sup>rd</sup> 2009: Meeting @ student societies for [http://www.chemische-binding.nl/ Chemistry] and [http://www.fmf.nl/?file=main.html&lang=.en Math, Physics, Computer Science and Astronomy]
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| - | *{{todo}} <b>October 30<sup>th</sup> to November 2<sup>nd</sup> 2009: Presentation @ The [https://2009.igem.org/ iGEM] 2009 [https://2009.igem.org/Jamboree Jamboree] - [http://whereis-beta.mit.edu/?mapterms=stata%20center&zoom=15&lat=42.36161990569666&lng=-71.09055519104004&open=object-32 MIT Stata] and [http://whereis-beta.mit.edu/?mapterms=lobby%2013&zoom=15&lat=42.35993922977393&lng=-71.092529296875&open=object-13 Lobby 13] in Cambridge, MA</b>
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| - | *{{todo}} October 26<sup>th</sup> 2009: Lecture @ [http://www.hanzeuniversity.eu/home/international Hanze University], Biology & Medical Laboratory Research and Bioinformatics students - room A257 [http://maps.google.nl/maps?q=Zernikeplein+7+Groningen&oe=utf-8&rls=org.mozilla:nl:official&client=firefox-a&um=1&ie=UTF-8&hq=&hnear=Zernikeplein+7,+9747+Groningen&gl=nl&ei=wwHPSor9A4OF-QaTkL2FAw&sa=X&oi=geocode_result&ct=title&resnum=1 Zernikeplein 11, Groningen]
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| - | *{{todo}} October 23<sup>rd</sup> 2009: Update Lecture @ the Bachelor course [http://www.rug.nl/ocasys/fwn/vak/show?code=WLB07010 Genes & Behaviour] - [http://maps.google.nl/maps?hl=nl&client=firefox-a&rls=org.mozilla:nl:official&hs=7wv&q=Haren+groningen&um=1&ie=UTF-8&hq=&hnear=Haren&gl=nl&ei=CSXDSsXoLJTc-Qbd7IXvCw&sa=X&oi=geocode_result&ct=image&resnum=1 Haren]
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| - | *October 19<sup>th</sup> 2009: [http://www.cs.rug.nl/~biehl/Coll/index.html Colloquium] @ [http://www.rug.nl/informatica/index Institute for Mathematics and Computing Science] - [http://maps.google.nl/maps?hl=nl&client=firefox-a&rls=org.mozilla:nl:official&hs=jGw&resnum=0&q=bernoulliborg%20Groningen%20Nijenborgh%209&um=1&ie=UTF-8&sa=N&tab=wl room 5161.0267 (Bernoulliborg), Groningen]
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| - | *October 12<sup>th</sup> 2009: Meeting @ Marine Biology cluster - [http://maps.google.nl/maps?hl=nl&client=firefox-a&rls=org.mozilla:nl:official&hs=7wv&q=Haren+groningen&um=1&ie=UTF-8&hq=&hnear=Haren&gl=nl&ei=CSXDSsXoLJTc-Qbd7IXvCw&sa=X&oi=geocode_result&ct=image&resnum=1 D225, Haren]
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| - | * October 7<sup>th</sup> 2009: Lecture @ the Bachelor course [http://www.rug.nl/ocasys/fwn/vak/show?code=WLB07010 Genes & Behaviour] - [http://maps.google.nl/maps?hl=nl&client=firefox-a&rls=org.mozilla:nl:official&hs=7wv&q=Haren+groningen&um=1&ie=UTF-8&hq=&hnear=Haren&gl=nl&ei=CSXDSsXoLJTc-Qbd7IXvCw&sa=X&oi=geocode_result&ct=image&resnum=1 D225, Haren]
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| - | * October 2<sup>nd</sup> 2009: Lunch meeting @ [http://www2.dhv.com/default.aspx DHV] - [http://maps.google.com/maps?f=q&source=s_q&hl=nl&geocode=&q=Laan+1914+no+35,+Amersfoort&sll=37.0625,-95.677068&sspn=54.357317,79.013672&ie=UTF8&hq=&hnear=Laan+1914+35,+3818+Amersfoort,+Utrecht,+Nederland&ll=52.134107,5.36828&spn=0.010405,0.01929&t=h&z=16&iwloc=r3 Groene zaal DHV, Amersfoort]
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| - | * October 1<sup>st</sup> 2009: Lunch meeting @ Life Science student society [http://www.glv-idun.nl/ GLV Idun] - [http://maps.google.nl/maps?hl=nl&client=firefox-a&rls=org.mozilla:nl:official&hs=7wv&q=Haren+groningen&um=1&ie=UTF-8&hq=&hnear=Haren&gl=nl&ei=CSXDSsXoLJTc-Qbd7IXvCw&sa=X&oi=geocode_result&ct=image&resnum=1 Groene Zaal, Haren]
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| - | *September 29<sup>th</sup> 2009: Meeting @ Applied physics student society [http://www.professorfrancken.nl/ TFV Professor Francken] - [http://maps.google.nl/maps?q=Nijenborgh%204%20NCC%20Complex&oe=utf-8&rls=org.mozilla:nl:official&client=firefox-a&um=1&hl=nl&ie=UTF-8&sa=N&tab=vl NCC complex VIP Room building 16, Groningen]
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| - | *[https://2009.igem.org/Team:Groningen/Notebook/24_September_2009 September 24<sup>th</sup> 2009]: Presentation @ 2nd Programme Day of the [http://www.kluyvercentre.nl/ Kluyver Centre] - [http://maps.google.nl/maps?q=Generaal+Foulkesweg+96+6703+DS+Wageningen&oe=utf-8&rls=org.mozilla:nl:official&client=firefox-a&um=1&ie=UTF-8&hq=&hnear=Generaal+Foulkesweg+96,+6703+Wageningen&gl=nl&ei=giXDSvfgDcrI-Qa53ojvCw&sa=X&oi=geocode_result&ct=image&resnum=1 Wageningse Berg, Wageningen]
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| - | *September 11<sup>th</sup> 2009: Presentation @ [http://www.rug.nl/gbb/studyatgbb/generalcourses/gbbsymposium2009 17th Annual] [http://www.rug.nl/gbb/index GBB] Symposium 2009 - [http://maps.google.nl/maps?oe=utf-8&rls=org.mozilla:nl:official&client=firefox-a&um=1&ie=UTF-8&q=Hampshire+hotel+Groningen+Radesingel+50,+9711+EK+Groningen&fb=1&gl=nl&hq=Hampshire+hotel&hnear=Groningen+Radesingel+50,+9711+EK+Groningen&cid=0,0,5400363645623663183&ei=eybDSq-jNojj-Qbz1PXuCw&sa=X&oi=local_result&ct=image&resnum=1 Hampshire hotel, Groningen]</div> -->
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[http://2009.igem.org/Team:Groningen/Project http://2009.igem.org/wiki/images/5/59/Title_front.png]
