Latest revision as of 11:46, 16 November 2009

[http://2009.igem.org/Team:Groningen/Project http://2009.igem.org/wiki/images/5/59/Title_front.png]

Heavy metal scavengers

Human health and the environment are endangered by heavy metal pollution in water and sediment. To battle this problem, a purification strategy, in which arsenic, zinc and copper are removed from water and sediment, was developed. This strategy encompasses a biological device in which E. coli bacteria accumulate metal ions from solutions, after which they produce gas vesicles and start floating. This biological device consists of two integrated systems: one for metal uptake and storage, the other for metal induced buoyancy. The uptake and storage system consists of a metal transporter and metal binding proteins (to reduce toxicity and increase accumulation). The buoyancy system is made up of a metal induced promotor in front of a gas vesicle gene cluster. The combination of both systems will enable the efficient cleaning of polluted water and sediment in a biological manner.

[http://2009.igem.org/Team:Groningen/Project http://2009.igem.org/wiki/images/a/a5/Enter.png]

[http://2009.igem.org/Team:Groningen/Project http://2009.igem.org/wiki/images/5/5f/Project_front.png]

[http://2009.igem.org/Team:Groningen/Team http://2009.igem.org/wiki/images/c/c1/Team_front.png]

[http://2009.igem.org/Team:Groningen/Modelling http://2009.igem.org/wiki/images/2/24/Model_front.png]

[http://2009.igem.org/Team:Groningen/HumanPractice http://2009.igem.org/wiki/images/5/5b/Ethics.png]

[http://2009.igem.org/Team:Groningen/Parts http://2009.igem.org/wiki/images/f/ff/Bricks.png]

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 <h1>Heavy metal scavengers<!-- with a vertical gas drive--></h1>
 Human health and the environment are endangered by heavy metal pollution in water and sediment. To battle this problem, a '''purification strategy''', in which arsenic, zinc and copper are removed from water and sediment, was developed. This strategy encompasses a biological device in which <i>E. coli</i> bacteria accumulate metal ions from solutions, after which they '''produce gas vesicles''' and '''start floating'''. This biological device consists of two integrated systems: one for metal uptake and storage, the other for metal induced buoyancy. The uptake and storage system consists of a [[Team:Groningen/Project/Transport|metal transporter]] and [[Team:Groningen/Project/Accumulation|metal binding proteins]] (to reduce toxicity and increase accumulation). The buoyancy system is made up of a [[Team:Groningen/Project/Promoters|metal induced promotor]] in front of a [[Team:Groningen/Project/Vesicle|gas vesicle gene cluster]]. The combination of both systems will enable the efficient cleaning of polluted water and sediment in a biological manner.
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-<li id="gas"></html>[[Team:Groningen/Project/Vesicle|Gas Vesicle]]<html></li>
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-*{{todo}} <b>October 30<sup>th</sup> to November 2<sup>nd</sup> 2009: Presentation @ The [https://2009.igem.org/ iGEM] 2009 [https://2009.igem.org/Jamboree Jamboree] - [http://whereis-beta.mit.edu/?mapterms=stata%20center&zoom=15&lat=42.36161990569666&lng=-71.09055519104004&open=object-32 MIT Stata] and [http://whereis-beta.mit.edu/?mapterms=lobby%2013&zoom=15&lat=42.35993922977393&lng=-71.092529296875&open=object-13 Lobby 13] in Cambridge, MA</b>
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-* October 1<sup>st</sup> 2009: Lunch meeting @ Life Science student society [http://www.glv-idun.nl/ GLV Idun] - [http://maps.google.nl/maps?hl=nl&client=firefox-a&rls=org.mozilla:nl:official&hs=7wv&q=Haren+groningen&um=1&ie=UTF-8&hq=&hnear=Haren&gl=nl&ei=CSXDSsXoLJTc-Qbd7IXvCw&sa=X&oi=geocode_result&ct=image&resnum=1 Groene Zaal, Haren]
-*September 29<sup>th</sup> 2009: Meeting @ Applied physics student society [http://www.professorfrancken.nl/ TFV Professor Francken] - [http://maps.google.nl/maps?q=Nijenborgh%204%20NCC%20Complex&oe=utf-8&rls=org.mozilla:nl:official&client=firefox-a&um=1&hl=nl&ie=UTF-8&sa=N&tab=vl NCC complex VIP Room building 16, Groningen]
-*[https://2009.igem.org/Team:Groningen/Notebook/24_September_2009 September 24<sup>th</sup> 2009]: Presentation @ 2nd Programme Day of the [http://www.kluyvercentre.nl/ Kluyver Centre] - [http://maps.google.nl/maps?q=Generaal+Foulkesweg+96+6703+DS+Wageningen&oe=utf-8&rls=org.mozilla:nl:official&client=firefox-a&um=1&ie=UTF-8&hq=&hnear=Generaal+Foulkesweg+96,+6703+Wageningen&gl=nl&ei=giXDSvfgDcrI-Qa53ojvCw&sa=X&oi=geocode_result&ct=image&resnum=1 Wageningse Berg, Wageningen]
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