Modelling

From 2009.igem.org

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==To find==
 
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PDB files of LOV domain, TrpR repressor => http://www.rcsb.org/pdb/home/home.do
 
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==To do==
 
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<br>- Set up day of starting modeling, do a planning for modeling => see with Matteo Dal Peraro
 
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<br>- Model allosteric interactions between LOVTAP & TrpR
 
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<br>- Do a mutational assay to change specificity of LOVTAP:
 
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Direct mutational assay: Insert mutation in specific sites thanks to the known structure of LOVTAP (already modeled on computer)
 
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<br>- Model the fusion of LOV domain with other transcription factors
 
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==To envisage ==
 
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<br>- Molecular mutationnal assay
 
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----
 
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
 
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!align="center"|[[Team:EPF-Lausanne|Home]]
 
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!align="center"|[[Team:EPF-Lausanne/Team|The Team]]
 
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!align="center"|[[Team:EPF-Lausanne/Project|The Project]]
 
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!align="center"|[[Team:EPF-Lausanne/Parts|Parts Submitted to the Registry]]
 
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!align="center"|[[Team:EPF-Lausanne/Modeling|Modeling]]
 
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!align="center"|[[Team:EPF-Lausanne/Notebook|Notebook]]
 
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!align="center"|[[Team:EPF-Lausanne/Lectures|Lectures]]
 
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!align="center"|[[Team:EPF-Lausanne/Team Management|Team Management]]
 
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|}
 

Latest revision as of 20:10, 10 July 2009