Team:Stanford/Notebook/Homeostasis

From 2009.igem.org

(Difference between revisions)
(New page: <html> <style> - ----- General: body { background: black; color: black; } </style> </html>   {{Template:Stanford_Main_Menu_0809}} {{Template:Stanford_Notebook_Menu_0809}} {|{...)
 
(One intermediate revision not shown)
Line 13: Line 13:
-
{|{{table}} width="800"
+
<html>
-
|-
+
<script language="JAVASCRIPT">
-
|style="background-color: #cdde95;" align="center"|
+
Today = new Date();
-
<!-- ## START calendar column -->
+
Jamboree = new Date("October 30, 2009");
-
<LNCalendar></LNCalendar>
+
msInADay = 1000 * 60 * 60 * 24;
-
<!-- ## END calendar column -->
+
display = Math.floor((Jamboree.getTime() - Today.getTime())/msInADay);
-
|align="center" style="background-color: #e5edc8;" |
+
document.write("<p style=\"text-align:center\">There are <b>" + display +" days left</b> until the Jamboree!</p>");
-
<!-- ## START search column: Place your logo here. Try keep it below 200px in width and 150px in height. ##  -->
+
</script>
-
[[Image:igem-logo-150px.png|150px]] <sitesearch>title=Search this project</sitesearch>
+
</html>
-
<!-- ## END search column  ## -->
+
{{:Team:Stanford/Notebook/Calendar}}
-
|-
+
 
-
|colspan="2" style="background-color: #F2F2F2;" align="right"|[[/Entry_Base|Customize your entry pages]] [[Help:Notebook/Project_Base/Customize_entry_page|<html><img src="/images/a/aa/Help.png" border="0" /></html>]]
+
 
-
|-
+
-
|colspan="2"|
+
==Project Description==
==Project Description==
The 2009 Stanford iGEM project centers on creating a device that will detect and respond to imbalances in specific subpopulations of T cells, a type of immune cell.  The two populations of T cells that we are particularly interested in are Th17 cells, a branch of helper T cells that promote inflammatory responses, and regulatory T cells (Tregs), crucial for the generation and maintenance of localized immunosuppression.  Distinct populations of Th17 cells and Tregs cells coexist and are reciprocally regulated in healthy tissue, and imbalances in the ratio of these lymphocytes have been implicated in a wide rage of autoimmune disorders including rheumatoid arthritis and irritable bowel diseases (IBD).  
The 2009 Stanford iGEM project centers on creating a device that will detect and respond to imbalances in specific subpopulations of T cells, a type of immune cell.  The two populations of T cells that we are particularly interested in are Th17 cells, a branch of helper T cells that promote inflammatory responses, and regulatory T cells (Tregs), crucial for the generation and maintenance of localized immunosuppression.  Distinct populations of Th17 cells and Tregs cells coexist and are reciprocally regulated in healthy tissue, and imbalances in the ratio of these lymphocytes have been implicated in a wide rage of autoimmune disorders including rheumatoid arthritis and irritable bowel diseases (IBD).  

Latest revision as of 09:31, 6 September 2009

 

Home Team Project Parts Notebook Archives

Team Notebook Individual Notebooks Weekly Descriptions


April
MTWTFSS
    [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/1_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 1] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/2_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 2] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/3_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 3] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/4_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 4] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/5_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 5]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/6_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 6] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/7_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 7] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/8_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 8] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/9_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 9] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/10_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 10] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/11_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 11] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/12_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 12]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/13_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 13] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/14_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 14] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/15_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 15] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/16_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 16] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/17_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 17] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/18_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 18] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/19_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 19]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/20_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 20] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/21_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 21] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/22_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 22] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/23_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 23] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/24_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 24] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/25_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 25] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/26_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 26]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/27_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 27] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/28_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 28] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/29_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 29] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/30_April_2009&preload=Team:Stanford/Notebook/Day&action=edit 30]
May
MTWTFSS
        [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/1_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 1] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/2_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 2] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/3_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 3]
[http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/4_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 4] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/5_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 5] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/6_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 6] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/7_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 7] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/8_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 8] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/9_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 9] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/10_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 10]
[http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/11_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 11] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/12_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 12] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/13_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 13] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/14_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 14] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/15_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 15] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/16_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 16] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/17_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 17]
[http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/18_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 18] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/19_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 19] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/20_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 20] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/21_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 21] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/22_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 22] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/23_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 23] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/24_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 24]
[http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/25_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 25] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/26_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 26] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/27_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 27] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/28_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 28] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/29_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 29] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/30_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 30] [http://2009.igem.org/wiki/index.php?title=Team:StanfordNotebook/31_May_2009&preload=Team:Stanford/Notebook/Day&action=edit 31]
June
MTWTFSS
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/1_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 1] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/2_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 2] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/3_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 3] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/4_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 4] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/5_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 5] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/6_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 6] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/7_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 7]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/8_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 8] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/9_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 9] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/10_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 10] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/11_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 11] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/12_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 12] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/13_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 13] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/14_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 14]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/15_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 15] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/16_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 16] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/17_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 17] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/18_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 18] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/19_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 19] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/20_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 20] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/21_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 21]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/22_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 22] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/23_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 23] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/24_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 24] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/25_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 25] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/26_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 26] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/27_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 27] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/28_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 28]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/29_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 29] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/30_June_2009&preload=Team:Stanford/Notebook/Day&action=edit 30]
July
MTWTFSS
    [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/1_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 1] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/2_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 2] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/3_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 3] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/4_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 4] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/5_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 5]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/6_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 6] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/7_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 7] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/8_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 8] [http://2009.igem.org/Team:Stanford/Notebook/9_July_2009 9] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/10_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 10] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/11_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 11] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/12_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 12]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/13_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 13] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/14_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 14] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/15_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 15] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/16_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 16] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/17_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 17] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/18_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 18] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/19_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 19]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/20_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 20] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/21_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 21] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/22_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 22] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/23_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 23] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/24_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 24] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/25_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 25] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/26_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 26]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/27_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 27] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/28_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 28] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/29_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 29] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/30_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 30] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/31_July_2009&preload=Team:Stanford/Notebook/Day&action=edit 31]
August
MTWTFSS
          [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/1_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 1] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/2_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 2]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/3_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 3] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/4_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 4] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/5_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 5] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/6_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 6] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/7_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 7] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/8_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 8] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/9_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 9]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/10_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 10] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/11_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 11] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/12_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 12] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/13_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 13] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/14_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 14] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/15_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 15] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/16_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 16]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/17_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 17] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/18_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 18] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/19_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 19] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/20_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 20] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/21_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 21] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/22_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 22] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/23_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 23]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/24_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 24] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/25_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 25] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/26_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 26] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/27_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 27] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/28_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 28] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/29_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 29] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/30_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 30]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/31_August_2009&preload=Team:Stanford/Notebook/Day&action=edit 31]
September
MTWTFSS
  [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/1_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 1] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/2_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 2] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/3_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 3] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/4_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 4] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/5_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 5] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/6_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 6]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/7_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 7] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/8_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 8] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/9_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 9] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/10_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 10] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/11_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 11] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/12_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 12] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/13_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 13]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/14_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 14] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/15_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 15] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/16_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 16] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/17_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 17] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/18_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 18] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/19_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 19] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/20_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 20]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/21_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 21] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/22_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 22] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/23_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 23] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/24_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 24] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/25_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 25] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/26_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 26] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/27_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 27]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/28_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 28] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/29_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 29] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/30_September_2009&preload=Team:Stanford/Notebook/Day&action=edit 30]
October
MTWTFSS
      [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/1_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 1] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/2_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 2] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/3_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 3] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/4_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 4]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/5_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 5] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/6_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 6] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/7_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 7] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/8_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 8] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/9_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 9] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/10_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 10] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/11_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 11]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/12_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 12] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/13_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 13] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/14_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 14] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/15_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 15] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/16_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 16] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/17_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 17] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/18_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 18]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/19_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 19] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/20_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 20] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/21_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 21] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/22_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 22] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/23_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 23] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/24_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 24] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/25_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 25]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/26_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 26] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/27_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 27] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/28_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 28] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/29_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 29] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/30_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 30] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/31_October_2009&preload=Team:Stanford/Notebook/Day&action=edit 31]
November
MTWTFSS
            [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/1_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 1]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/2_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 2] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/3_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 3] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/4_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 4] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/5_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 5] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/6_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 6] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/7_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 7] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/8_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 8]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/9_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 9] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/10_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 10] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/11_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 11] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/12_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 12] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/13_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 13] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/14_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 14] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/15_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 15]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/16_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 16] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/17_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 17] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/18_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 18] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/19_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 19] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/20_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 20] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/21_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 21] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/22_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 22]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/23_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 23] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/24_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 24] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/25_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 25] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/26_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 26] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/27_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 27] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/28_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 28] [http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/29_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 29]
[http://2009.igem.org/wiki/index.php?title=Team:Stanford/Notebook/30_November_2009&preload=Team:Stanford/Notebook/Day&action=edit 30]


Project Description

The 2009 Stanford iGEM project centers on creating a device that will detect and respond to imbalances in specific subpopulations of T cells, a type of immune cell. The two populations of T cells that we are particularly interested in are Th17 cells, a branch of helper T cells that promote inflammatory responses, and regulatory T cells (Tregs), crucial for the generation and maintenance of localized immunosuppression. Distinct populations of Th17 cells and Tregs cells coexist and are reciprocally regulated in healthy tissue, and imbalances in the ratio of these lymphocytes have been implicated in a wide rage of autoimmune disorders including rheumatoid arthritis and irritable bowel diseases (IBD).

Our goal is to sense and correct such imbalances in individuals suffering from IBD by creating an Escherichia coli-based bacterial device that polarizes the differentiation of lymphocyte precursors along either the Th17 or Treg lineage. Our device will consist of two parts. The first part, our anti-inflammatory device, will control dangerous localized inflammation in the gut by detecting a byproduct linked to Th17-driven inflammation, nitric oxide, and excreting retinoic acid, a marker that inhibits the generation of Th17 cells. Likewise, the second, anti-immunosuppressive device, regulates Treg populations by detecting an analog of tryptophan, a target substrate of an enzyme involved in Treg immunosuppression, and secretes interleukin-6, a cytokine that inhibits Treg development.

We envision our proposed machine as a novel and directed probiotic therapy that will act at the interface between commensal bacteria and human lymphocytes while integrating cutting-edge immunology with synthetic biology.

Notes and Comments

  • [Please leave comments here!!!]



|- |colspan="2" style="background-color: #F2F2F2;"| Template:LnNotebookRecentChanges2 |}