Team:Groningen

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|Welcome to the Wiki of the iGEM Groningen team! We are an interdisciplinary team of [[Team:Groningen/Team|11 enthusiastic students]] from the [http://www.rug.nl/ University of Groningen] situated in the not-too-big city of [http://portal.groningen.nl/en/startpagina Groningen] in [http://maps.google.com/maps?f=q&source=s_q&hl=en&geocode=&q=Groningen&sll=53.281349,6.689459&sspn=0.007261,0.018926&ie=UTF8&z=12&iwloc=A the north of the Netherlands]. You can also follow us on [http://twitter.com/igemgroningen twitter]!
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<h1>Heavy metal scavengers<!-- with a vertical gas drive--></h1>
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Human health and the environment are endangered by heavy metal pollution in water and sediment. To battle this problem, a '''purification strategy''', in which arsenic, zinc and copper are removed from water and sediment, was developed. This strategy encompasses a biological device in which <i>E. coli</i> bacteria accumulate metal ions from solutions, after which they '''produce gas vesicles''' and '''start floating'''. This biological device consists of two integrated systems: one for metal uptake and storage, the other for metal induced buoyancy. The uptake and storage system consists of a [[Team:Groningen/Project/Transport|metal transporter]] and [[Team:Groningen/Project/Accumulation|metal binding proteins]] (to reduce toxicity and increase accumulation). The buoyancy system is made up of a [[Team:Groningen/Project/Promoters|metal induced promotor]] in front of a [[Team:Groningen/Project/Vesicle|gas vesicle gene cluster]]. The combination of both systems will enable the efficient cleaning of polluted water and sediment in a biological manner.  
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[[Image:Groningen_team2009_Martini.jpg|200px|thumb|right|[Team:Groningen/Team|Our team!]]
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[[Team:Groningen/Project|Our project]] is creating buoyant, metal accumulating bacteria to filter (heavy) metals from water. To ensure we have at least some success we have split up our project in four independent subprojects:
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|{{linkedImage|Team_front.png|Team:Groningen/Team}}
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*[[Team:Groningen/Project/Transport|Metal transport]]
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|{{linkedImage|Ethics.png|Team:Groningen/HumanPractice}}
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*[[Team:Groningen/Project/Accumulation|Metal accumulation]]
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*[[Team:Groningen/Project/Vesicle|Gas Vesicle]]
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*[[Team:Groningen/Project/Promoters|Metal sensitive promoters]]
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And don't forget to have a look at our [[Team:Groningen/Project_Plan|project plan]] (and other [[:Category:Team:Groningen/Disciplines/Project_Management|related documentation]]) as it is being developed. Also our [[:Category:Team:Groningen/Roles/Modeller|modellers]] have made a survey of some of the [[Team:Groningen/Brainstorm/Modelling|modelling technologies]] that have been used, our [[:Category:Team:Groningen/Roles/Treasurer|financial geniuses]] are raising funds and our [[:Category:Team:Groningen/Roles/Implementer|lab specialists]] are reading all sorts of [[Team:Groningen/Literature|interesting stuff on synthetic biology]].
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'''Note for our team members:''' Layout ideas can be proposed/discussed/tried out [[Team:Groningen/Layout_Ideas|here]] and ideas for future work written down at [[Team:Groningen/Future]].
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<center>[[Team:Groningen/Publicity| PUBLICITY FOR iGEM FROM GRONINGEN]]</center>
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Latest revision as of 11:46, 16 November 2009

[http://2009.igem.org/Team:Groningen/Project http://2009.igem.org/wiki/images/5/59/Title_front.png]

Heavy metal scavengers

Human health and the environment are endangered by heavy metal pollution in water and sediment. To battle this problem, a purification strategy, in which arsenic, zinc and copper are removed from water and sediment, was developed. This strategy encompasses a biological device in which E. coli bacteria accumulate metal ions from solutions, after which they produce gas vesicles and start floating. This biological device consists of two integrated systems: one for metal uptake and storage, the other for metal induced buoyancy. The uptake and storage system consists of a metal transporter and metal binding proteins (to reduce toxicity and increase accumulation). The buoyancy system is made up of a metal induced promotor in front of a gas vesicle gene cluster. The combination of both systems will enable the efficient cleaning of polluted water and sediment in a biological manner.

[http://2009.igem.org/Team:Groningen/Project http://2009.igem.org/wiki/images/a/a5/Enter.png]
[http://2009.igem.org/Team:Groningen/Project http://2009.igem.org/wiki/images/5/5f/Project_front.png] [http://2009.igem.org/Team:Groningen/Team http://2009.igem.org/wiki/images/c/c1/Team_front.png] [http://2009.igem.org/Team:Groningen/Modelling http://2009.igem.org/wiki/images/2/24/Model_front.png] [http://2009.igem.org/Team:Groningen/HumanPractice http://2009.igem.org/wiki/images/5/5b/Ethics.png] [http://2009.igem.org/Team:Groningen/Parts http://2009.igem.org/wiki/images/f/ff/Bricks.png]
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