"
Team:DTU Denmark/Team
From 2009.igem.org
(→Who we are) |
(→Who we are) |
||
| (8 intermediate revisions not shown) | |||
| Line 56: | Line 56: | ||
'''Advisors:''' | '''Advisors:''' | ||
| - | *''' Advisor 1''': Kiran Raosaheb Patil | + | *''' Advisor 1''': Kiran Raosaheb Patil (assistant professor) |
| - | *'''Advisor 2''': | + | *'''Advisor 2''': Bjarne Gram Hansen (post.doc) |
| - | *''' | + | *'''PhD Student 1''': Ana Rita Brochado (PhD student) |
| + | *'''PhD Student 2''': Simon Carlsen (PhD student) | ||
| + | |||
| Line 73: | Line 75: | ||
| | | | ||
<gallery> | <gallery> | ||
| - | Image: | + | Image:mads.png|Mads |
| - | Image: | + | Image:hans.png|Hans |
| - | Image: | + | Image:bjorn.png|Bjørn |
| - | Image: | + | Image:christian.png|Christian |
| - | + | Image:claudia.png|Claudia | |
| - | Image: | + | Image:lars.png|Lars |
</gallery> | </gallery> | ||
|} | |} | ||
| Line 84: | Line 86: | ||
== '''What we did''' == | == '''What we did''' == | ||
| - | + | The aim of this project is to model and construct a molecular NAD+/NADH ratio sensing system in Saccharomyces | |
| - | + | cerevisiae by using a synthetic biology approach. The sensor will work as an inducible transcription factor, being | |
| + | active only at certain levels of the NAD+/NADH ratios. By coupling the sensor to the expression of a reporter | ||
| + | gene, the system can be used for monitoring the NAD+/NADH redox poise in vivo. This will be beneficial for research | ||
| + | in many areas including productivity optimization and cancer research. Furthermore, the sensor will be | ||
| + | coupled to the biosynthesis of a gene-product (e.g. insulin), in an attempt to improve and prolong chemostat | ||
| + | fermentation processes by producing in small bursts, thereby limiting cell stress. | ||
== '''Where we're from''' == | == '''Where we're from''' == | ||
| + | We are a team of engineering student from the Technical University of Denmark, located in Lyngby north of the nations capitol, Copenhagen. | ||
Latest revision as of 13:51, 20 June 2009
| You can write a background of your team here. Give us a background of your team, the members, etc. Or tell us more about something of your choosing. |  |
|
Tell us more about your project. Give us background. Use this is the abstract of your project. Be descriptive but concise (1-2 paragraphs) |  Your team picture |
| Team Example 2 |
| Home | The Team | The Project | Parts Submitted to the Registry | Modeling | Notebook |
|---|
(Or you can choose different headings. But you must have a team page, a project page, and a notebook page.)
Who we are
|
Advisors:
Students:
|
|
What we did
The aim of this project is to model and construct a molecular NAD+/NADH ratio sensing system in Saccharomyces cerevisiae by using a synthetic biology approach. The sensor will work as an inducible transcription factor, being active only at certain levels of the NAD+/NADH ratios. By coupling the sensor to the expression of a reporter gene, the system can be used for monitoring the NAD+/NADH redox poise in vivo. This will be beneficial for research in many areas including productivity optimization and cancer research. Furthermore, the sensor will be coupled to the biosynthesis of a gene-product (e.g. insulin), in an attempt to improve and prolong chemostat fermentation processes by producing in small bursts, thereby limiting cell stress.
Where we're from
We are a team of engineering student from the Technical University of Denmark, located in Lyngby north of the nations capitol, Copenhagen.
