Team:EPF-Lausanne/Survey

Human Practices - Survey

Survey

We sent out a survey to try to answer questions mainly about the following two aspects of biology and ethics :

- Association of the level of knowledge with the feelings towards synthetic biology

- Opinion of people on whether they think humans have the right to manipulate genes, and similar issues

Here is the [http://spreadsheets.google.com/embeddedform?key=tfRE0LnWAJbEowo3w7zwFMw Survey]

It consists of 16 little questions, all multiple choices.

• The 4 first questions are general information about the person answering the survey (age, sex, education level and scientific background).

• Then we have 2 questions about synthetic biology, to see if people know what it is and what kind of concepts they associate with it.

• The 4 next questions are here to evaluate the level of knowledge about some basic biologic concepts.

• The 6 last questions are here to collect the opinion of people about cloning, whether human have the right to kill animals and similar ethical issues.

Overview

In this part we wanted to gather the opinion of various people. Here are highlighted the major conclusions of this survey :

• We managed to have access to opinion of people of different age group and different background in a very short time. Our survey thus seems representative.

• We can see the opinions are very divided. We were surprised of certain answers.

• The knowledge question were very well answered.

• Many people have a negative or neutral feeling about cloning, and even more if they don't come from a scientific domain.

Results

We closed the survey on 16th of October, we have 469 answers to the survey.

How old are you?

The majority of our answers come from people between 18 and 21 years old.

What is your sex?

However, we manage to find a pretty representative panel of people in regard to their sex.

What is your study level?

While the majority of asked people have come to the end of high school, we have people with all kind of study levels.

Are you in a scientific domain?

However, most of them come from a scientific area, in a large sense.

Do you know what Synthetic Biology is?


The correlation between being in a scientific domain and knowing what Synthethic Biology gives us -1, which means there is no correlation between the two, and being a scientist does not involves a better knowledge of what is syntehtic biology.

Tick 3 words that best explain what is Synthetic Biology

The three most chosen words are:

• Cloning (215 votes = 46%)
• Genetics (317 votes = 68%)
• Engineering (191 votes = 41%)

We have to highlight the fact that GMO is very close with 171 votes (36%). Note that people had to choose 3 words, so the sum of percentages may add to up than 100%.

The following percentages are : GMO 37%, Simulation 20%, Bacteria 19%, Informatics 17%, Plastic 16%, Illness 12%, Textile 10%, Experimentation on animals 10%, Botanics 7%.

We have some people that have apparently no idea of what synthetic biology is. For example people that choose textile or plastic did it because it sounds like synthetic...

Do plants have genes?


This question (as the two following ones) intend to evaluate basic knowledges in biology: we were pretty happy to see that people knows for a great majority basic biology.





Brothers and sisters have the same genetic material, only their environment make them differnet: Right or wrong?




This is the question that was the least well answered. 52 persons picked the wrong answer. There was 82 persons coming from an non-scientific area, which means that at least one third of them had some basic genetic knowledge and could answer this question.

All bacteria elicit diseases: Right or wrong?

This question was particularly well answered. It seems that people mostly know that there are some commensal bacteria.

What are GMO?


63% of the answers were Transgenic organisms. Then comes Organisms resulting from the mating of different species with 17%, Plants which have had their growth rate optimized with 11%, then Modified organisms that contaminate natural species got 8% of the answers. Finally we had still 1% of answers Containers containing a compressed video flux and/or an OGG audio flux (which is a true difinition !!).

What is your impression when one says "cloning"?

It is interesting to see that opinion are extremely divided, the majority being either neutral or negative (with 41% of the answers). Then comes the negative impression with 37% and finally only 22% of the people had a positive impression when they hear the word cloning.

Do you think that humans have the right to manipulate genetic material?

53% of the people thought "rather yes", then we have 21% of "rather no", 15% of "yes, absolutely", 5% of "absolutely not" and 5 % of "I don't have an opinion on the subject". Again we have a divided opinion on the subject, it would be interesting to see the correlation between the age or the scientific area (or not) and this opinion.

Do you think that humans have the right to kill animals for scientific research?

Again the opinion is very distributed, with 37% of "Rather yes", 30% of "Rather no", 14% of "Absolutely not", 13% of "Yes, absolutely" and 5% of "I don't have an opinion on the subject". It is interesting to see that, compared to see the last question, we have significantly more "Absolutely not" and less "Rather yes". It seems that the animal cause is still a sensitive subject for certain person !

Do you think that scientific research in the field of biology is:


The answers to this question were mostly divided into two : 54% of "Good, if one puts limits to it and it remains under control" and 42% of "Necessary, to understand the world around us". Then comes "Dangerous, because it could go too far" with 3% and 1% "Useless and innessential, our money could be better used elsewhere". Thus, very few people are totally against research and most of them understand that it is important... 54% think it is very important to control it very well and 42% just think it is necessary.

Do you think that scientific research in the field of biology goes against your religious/cultural principles?


53% of the answers were "Not at all", 26% "Rather no" and 11% "I don't have an opinion on the subject". Then it is interesting to see that there is still 7% of "Rather yes" and 2% of "Yes, absolutely", which makes a total of 46 persons that see some conflicts between scientific research and their religious/cultural principles. It will be interesting to see who is this population.

What do you think of the act of using the living to ends of industrial production?



Here more than one answer was possible. The answers were very variable. We got 59% of "Laws are necessary to control it", 39% of "It is good, but only in certain cases", 28% of "It's useful", 20% of "It's dangerous", 14% of "It's immoral", 13% of "It's necessary", and 8% of "I don't have an opinion on the subject".

Analysis of the results

We will investigate the relationship between knowledge, opinion and background of the people. To do this analysis, we used the excel functions, as the result of our survey is in the excel form. Here is the detailed analysis :

Scientific background and level of knowledge

We first divided our sample between people which have a scientific background and those who are not. For each group, we tested they basic knowledge in biology with 3 questions: Do plants have gene?, Brothers and sisters have the same genetic material, only their environment make them different: Right or wrong?, All bacteria elicit diseases: Right or wrong?. If a person responded right to the three questions, we consider it has a basic knowledge. The result are shown in this table:

• Knowledge vs people being in the science field

	In the scientific domain
Knowledge	Yes	No
Yes	199	35
No	193	50
Total	477
	50,8%	41.2%

50,8% of people saying that they are in the scientific domain have basic knowledge in biology, while 41% of those who are not have nevertheless basic knowledge.

So there is a little difference between people which are in scientific domain and those who aren't, but not as much as we thought. It can come from the fact that some high school students of 15 years old can be oriented in a scientific domain but they haven't studied this kind of knowledge yet.

Scientific background and opinion

We first looked at the answers to the questions : Do you think that humans have the right to manipulate genetic material?

• Genetic material vs people in a scientific domain

	in a scientific domain
Genetic material	Yes	No
Yes	278	46
No	98	34
I don't know	16	5
Total	477
	70,9%	54,1%
Total	456 without the I don't know
	73,9%	57,5%

So 70,9% of people saying that they belong to a scientific domain are favorable to genetic material manipulation, wile on the other hand 54,1% of those who are not are favorable. If we don't consider people which are without opinion, the satatistics doesn't change.

So we can say that scientists have a tendancy to have a positive opinion about gene manipulation.

Then we can look at the question : Do you think that humans have the right to kill animals for scientific research?

• Right to kill animals vs people in science

	in science
Right to kill animals?	Yes	No
Yes	203	36
No	169	44
I don't know	20	5
Total	477
	51,8%	42,4%
Total	452 without the I don't know
	54,6%	45%

51,8% of people in the scientific domain are favorable to killing animals for sience, while 42,4% of those who are not are favorable to it. The number of people without opinion don't change statistics.

There is almost no difference in opinion between people from science and not science domain. Even though there are a bit more people favorable in science that people in not science domain. But we can see that the question about using animals for research is still important in our society.

We also looked at the opinion about cloning.

• Opinion about cloning vs Scientific domain

	In a scientific domain
Opinion	Yes	No
Positive	95	10
Negative	133	46
Neutral	164	29
Total	477
Total	24,2%	11,8%
Total	284 without the I don't know
	41.7%	17.9%

24,2% of people in a scientific field are favorable to cloning, while only 11,8% of those who are not are pros. And if we

So there is a very small correlation, again scientists have a tendancy to have a positive opinion about it but isn't very significant.

Finally, the question Do you think that scientific research in the field of biology goes against your religious/cultural principles?. A Not at all and rather no gives a 1, the rest a 0. The correlation is p = 0.011483668. So there is no correlation.

Sex and opinion

Then we wondered if there was a certain type of correlation between the sex and certain opinion. For example, it could be believed that woman are more attached to some sentimental causes such as the animal one.

We looked at the question Do you think that humans have the right to kill animals for scientific research?. If the person answering was a woman, we put +1 and if it is a man 0. If the answer is Rather no or Absolutely we put +1. The correlation is : 0.194965015. So there a small tendancy : more than half of the woman think that humans don't have the right to kill animals for scientific research.

Age and knowledge

We could also think that older people answer better the question. We will thus do the correlation between the younger group age and the bad responses. If a person is between 14-17 years old, it give 1 point otherwise 0. If the knowledge score is less than 4, it also gives one point (otherwise 0). p = 0.023350723. So there is almost no correlation.

Sex and knowledge

Do women have less knowledge in science ?? A knowledge score < 4 is correlated with being a woman. We find :

p = 0.12600463

So there is no correlation between being a woman and being less aware in sciences.

If we compute the correlation coefficient between being a man and have a knowledge score <4, we get p = -0.12600463 (which is logical). So a less extended knowledge in sciences is more correlated with being a woman, even if it isn't very significant.

Knowledge of what is synthetic biology and opinions

As we have seen before, the correlation between some opinions and an orientation in a scientific domain is not as high as we expected. This could be due to the fact that the "orientation in a scientific area" is a very broad term. For example, students of 15 years that took as option mathematics and physics (but only had a month of these classes) would answer yes to this question, but they don't have a full scientific formation... Here we will rather do the correlation between the people that know what synthetic biology (hoping they didn't pick yes randomly) and their opinion.

First : if the people know what synthetic biology is, it gives a +1 point, if they don't know 0 point. Then if they have a positive opinion about cloning, it gives a +1, or neutral or negative opinion gives a 0. The result is : p = 0.111878207. It is slightly lower than the 0.11517346 of the correlation with the scientific orientation. As very few people know what synthetic biology is, maybe they only know it by chance (family member part of iGEM, read it in a newspaper,...) but it is apparently not a good indicator of "scientific opinion".

• Cloning vs people being in the synthetic biology domain

	In the synthetic biology domain
Cloning	Yes	No
Yes	44	61
No	109	263
Total	477
	28,8%	18.8%

So 28% of people saying that they know what synthetic biology is are favorable to cloning, while 18% of the one who do not knopw what synthetique biology are favorable.

• Cloning vs people in synthetic biology domain

	in synthetic biology domain
Cloning	Yes	No
Positive	44	61
Negative	39	140
Neutral	70	123
Total	284 without the Neutral
	53%	30,3%

53% of people knowling what Synthetic Biology is are favorable to cloning, while 30,3% of those who don't are favorable.

• Sex vs killing animals

	Sex
Kill animals?	Male	Female
Yes	143	96
No	109	263
I don't know	11	14
Total	452 without the I don't know
	62,7%	42,9%

Nearly 63% of men answered they were favorable to kill animals for science, while only 42,3% of women are!

• Genetic material vs people in synthetic biology domain

	in synthetic biology domain
Genetic material	Yes	No
Yes	124	200
No	21	108
I don't know	8	16
Total	453 without the I don't know
	85,5%	64,9%

85,5% of people saying that they know what synthetic biology is are favorable to genetic manipulation, while 64,9% of those who don't know are pros.

• Kill animals vs people in science

	in science
Kill animals?	Yes	No
Yes	203	36
No	169	44
I don't know	20	5
Total	452 without the I don't know
	54,6%	45%

54,5% of people in the scientific domain are favorable to killing animals for sience, while 45% of those who are not are favorable to it.

• Knowledge vs Young

	Young
Knowledge	Yes	No
Yes	39	195
No	45	198
Total	477
Total	46,4%	49,6%

46,4% of young people have basic knowledge, while 49,6% of older people have.

• Knowledge vs sex

	Sex
Knowledge	Male	Female
Yes	128	106
No	111	132
Total	477
Total	53,6%	44,5%

53% of men have basic knowledge in the biology field, while 44,5% of women have.

• Cloning vs Scientific domain

	in a scientific domain
Cloning	Oui	No
Yes	95	10
No	297	75
Total	477
Total	24,2%	11,8%

24,2% of people in a scientific field are favorable to cloning, while only 11,7% of those who are not are pros.

• Religion vs Science

	In a scientific domain
Religion	Yes	No
Yes	38	9
No	314	65
I don't know	40	11
Total	426 without the I don't know
	10,8%	12,2%

10,8% of scientists think biology is going against their personal believes or religion, while 12,2% of those who are not think the same (while excuding people without opinion).

Conclusion

We see that the opinions are very divided in the major questions we asked. Even if over than 80% of the participants were oriented in a scientific domain, they don't all have positive opinion about cloning, they don't all think that humans have the right to manipulate genetic material etc. So we have very diverse opinions !

We were surprised that as many people answered correctly to the knowledge questions.

No major correlations were discovered : even if being in a scientific domain "predisposes" to certain opinions, this is not strongly the case. It is the same for all the other relationships we thought would occur between different age groups, sex or orientation. So globally, we can conclude that clichés aren't always true! Indeed, many people might imagine that biologists would think that cloning is less of an issue, just because they deal with cloning daily. From this survey, however, we can see that this is not necessarily true: the area in which people work perhaps shows what they are interested in, but it apparently doesn't change their beliefs and convictions. In general, it is a rather reassuring conclusion, it demonstrates that scientifics remain critical towards what they are working on, and that they do understand the issues that might arise from areas such as synthetic biology.