Team:McGill/Modeling
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+ | =='''Introduction'''== | ||
+ | Many models examining intercellular signaling do not take into account the separation distances of the signaling bodies. We use a partial differential equation (PDE) based model to gain insight into spatially heterogeneous activation-inhibition intercellular signaling. | ||
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+ | Two types of signaling molecules exist: activating and inhibiting. Each molecule is synthesized by a unique strain of cells and affects the synthesis rate of the other strain. | ||
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+ | [[Image: Mcgill09Projectfig1.png|frame|center|Figure 1 – Activation-inhibition intercellular signaling – Activating molecule (A) synthesized and diffuses to increase synthesis of inhibiting molecule (B) in secondary strain. Inhibiting molecule also diffuses back to initial cell and decreases synthesis of activating molecule.]] | ||
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+ | This is modeled using the following system of PDEs: | ||
+ | [[Image: Mcgill09PDEs.png|frame|center]] |
Revision as of 05:40, 21 October 2009
Introduction
Many models examining intercellular signaling do not take into account the separation distances of the signaling bodies. We use a partial differential equation (PDE) based model to gain insight into spatially heterogeneous activation-inhibition intercellular signaling.
Two types of signaling molecules exist: activating and inhibiting. Each molecule is synthesized by a unique strain of cells and affects the synthesis rate of the other strain.
This is modeled using the following system of PDEs: