Team:Chiba

E.coli Time Manager Since 2008

Welcome to the Chiba team Wiki for iGEM 2009!

Team Photo

I’ll introduce Team Chiba to you. Team Chiba joined iGEM in 2006. Its members belong to The Dep. of Chemistry and so we did not know much biology. The members therefore had to start from studying the basics of biology. This was the characteristic, but what I believe to be the biggest weak point for the Team.

This year, However, Team Chiba has a member who belongs to the Dep. of biology! He is nothing but an undergraduate student but I expect that the energy of our team will be made better by his existence.

This years project is making the most of last year's project. Last year, we tried to devise a series of delay-switches by designing a "switching consortia". We got limited, in success in generating delay swithces, but I think that there is a great deal of room for improvement.

The Registration of our team is very late, in June, and our team has only 5 people. I don't know what will become of our team, but I think the best for our team that all members our team enjoy to the full! Thank you.

Project - E. coli Time Manager Since 2008

We are constructing delay switches to control/preset the timing of target gene expression.

Our project uses two classes of bacteria: senders and receivers. Senders produce signaling molecules, and receivers are activated only after a particular concentration of this molecule is reached. The combinatorial use of senders/receivers allows us to make a‘switching consortium’which activates different genes at the preset times.

千葉のタイマーの特徴は、細菌どうしの化学通信機構を利用した「時間合わせ」機能です。リアルタイムに化学通信を行なうことで、何万もの細胞が、いま感じている時間を共有することができます。このため細胞集団は、一糸乱れず同時にアクションを起こせるわけです。このタイマーを使って色々なタイミングで細胞を「色変化」させ、細胞集団に様々なアニメーションを描かせたい、これが私たちの最終目標です！

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