Team:HKU-HKBU/Acknowledgments

From 2009.igem.org

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=Overview=
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Many of the non-invasive medications nowadays include uses of nanorobots which promise to an innovating technique for surgical instrumentation, diagnosis and drug delivery. However, many of them lack a reliable propulsion power source to operate and this critical crisis remains one of the biggest obstacles to the extensive use of nanorobots in medical treatment. Our "Bactomotor" aims to overcome these problems and bring a foundational and pioneering advancement.
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In the design of our model, it is mainly divided into '''THREE''' modules:
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We would like to say a huge thank you to the followings for their warm support to our team:
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# We need to select a strain of ''E. coli'' that possesses flagella as well as a fast-swimmer. In terms of swimming, the strain must swim in a unidirectional movement while non-tumbling.
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# The speed of swimming can be regulated by specific reagents.
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# The strain needs to express a protein called Streptavidin on its outer membrane. This protein can bound very strongly to the biotin-coated motor and hence attaching the Streptavidin-expressing ''E. coli'' to the motor.
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The application of "Bactomotor" will be extremely valuable and immense when comes to nanorobots-assisted surgery or any medical treatment that requires nanorobots for body inspection as they provide a non-invasive method. A few examples are given below:
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# Lee Ka Shing Faculty of Medicine, University of Hong Kong ;Faculty of Science, University of Hong Kong and the Hong Kong Baptist University for making our trip to MIT becomes possible!
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* Selective drug delivery to target cells, increasing bioavailability and minimalizing systemic side effects.
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# Everyone in the Department of Biochemistry, University of Hong Kong for providing lab spaces to us and tolerate our excess noise when performing labs!
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* Endarectomy of small arteries/arterioles/capillaries as treatment for atherosclerosis not reachable by catheters.  
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# Bio-rad and Invitrogen for their generous financial support towards our research expenses.
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* Lysis of blood clot in small arteries in brain as treatment for stroke
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# Genestimes Technology for providing gifts to our Human Practices group.
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# Delta Airline for their sponsor on our air tickets.
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# Many postgraduates who had suffocated by our numerous questions and requests.
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# Everyone who devoted their whole summer to this project (It’s hard, you know)!
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# All the people who have helped us in any way throughout the past few months.
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* Everybody we missed above.
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Outside medicine, another potential application of the bio-motor is to generate electricity, thus providing promising alternative renewable energy sources to our increasing electricity-demanding world, especially to those developing countries. Nevertheless, these fruitful findings hopes to act as some valuable stepping stone for us to develop further discoveries and even more sophisticated products in coming years.
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Finally, a '''massive''' thank you must be said to our supervisors, Dr. JD Huang, Dr. JJ Wang and Dr. YQ Song for their patient, help and many efforts they have offered during the past few months.  
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Revision as of 06:59, 20 October 2009

Acknowledgments

We would like to say a huge thank you to the followings for their warm support to our team:

  1. Lee Ka Shing Faculty of Medicine, University of Hong Kong ;Faculty of Science, University of Hong Kong and the Hong Kong Baptist University for making our trip to MIT becomes possible!
  2. Everyone in the Department of Biochemistry, University of Hong Kong for providing lab spaces to us and tolerate our excess noise when performing labs!
  3. Bio-rad and Invitrogen for their generous financial support towards our research expenses.
  4. Genestimes Technology for providing gifts to our Human Practices group.
  5. Delta Airline for their sponsor on our air tickets.
  6. Many postgraduates who had suffocated by our numerous questions and requests.
  7. Everyone who devoted their whole summer to this project (It’s hard, you know)!
  8. All the people who have helped us in any way throughout the past few months.
  • Everybody we missed above.

Finally, a massive thank you must be said to our supervisors, Dr. JD Huang, Dr. JJ Wang and Dr. YQ Song for their patient, help and many efforts they have offered during the past few months.

Sponsors

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