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Team:IPN-UNAM-Mexico/Safety
From 2009.igem.org
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Our current project raised no safety issues, since it doesn’t involve any future use in humans, and it is not contemplated to be released to the envroment, and the risk is very low because all the bacterial colonies and reagents were properly handled, as taught at the very beginning by our advisors. | Our current project raised no safety issues, since it doesn’t involve any future use in humans, and it is not contemplated to be released to the envroment, and the risk is very low because all the bacterial colonies and reagents were properly handled, as taught at the very beginning by our advisors. | ||
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Although the genes of both the lux and las operon are sometimes involved in virulence, to our knowledge these quorum sensing systems in E. coli are unable to increase the pathogenicity risks, since all the bacterial strains we used are non pathogenic. However E. coli is known to use a different quorum sensing system, the lsr operon; and even they are showed to be capable of sensing other species signals, the domesticated strain DH5a does not respond to these signals increasing its pathogenicity. | Although the genes of both the lux and las operon are sometimes involved in virulence, to our knowledge these quorum sensing systems in E. coli are unable to increase the pathogenicity risks, since all the bacterial strains we used are non pathogenic. However E. coli is known to use a different quorum sensing system, the lsr operon; and even they are showed to be capable of sensing other species signals, the domesticated strain DH5a does not respond to these signals increasing its pathogenicity. | ||
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Revision as of 22:56, 21 October 2009
Safety
Our current project raised no safety issues, since it doesn’t involve any future use in humans, and it is not contemplated to be released to the envroment, and the risk is very low because all the bacterial colonies and reagents were properly handled, as taught at the very beginning by our advisors.
Although the genes of both the lux and las operon are sometimes involved in virulence, to our knowledge these quorum sensing systems in E. coli are unable to increase the pathogenicity risks, since all the bacterial strains we used are non pathogenic. However E. coli is known to use a different quorum sensing system, the lsr operon; and even they are showed to be capable of sensing other species signals, the domesticated strain DH5a does not respond to these signals increasing its pathogenicity.
