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Team:ULB-Brussels/Project
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Whether you want to stop a leaking ship's hull, or repair a fractured bone, you need a strong adhesive. Our project aims at producing a new generation of glue. In contrast to most glues, our glue is natural, biodegradable, efficient on wet surfaces and is composed of polysaccharides naturally produced by the <i>Caulobacter crescentus</i> bacterium. Using BioBrick<sup>TM</sup> standard biological parts, we engineered a synthetic <i>Escherichia coli</i> strain which synthesizes this adhesive material. To improve our expression system, we plan to use a new plasmid stabilization technique, the Staby<sup>TM</sup> system. This system stabilizes expression plasmid without using antibiotics, which is of major concern in large-scale production of biological materials. | Whether you want to stop a leaking ship's hull, or repair a fractured bone, you need a strong adhesive. Our project aims at producing a new generation of glue. In contrast to most glues, our glue is natural, biodegradable, efficient on wet surfaces and is composed of polysaccharides naturally produced by the <i>Caulobacter crescentus</i> bacterium. Using BioBrick<sup>TM</sup> standard biological parts, we engineered a synthetic <i>Escherichia coli</i> strain which synthesizes this adhesive material. To improve our expression system, we plan to use a new plasmid stabilization technique, the Staby<sup>TM</sup> system. This system stabilizes expression plasmid without using antibiotics, which is of major concern in large-scale production of biological materials. | ||
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== Biological model == | == Biological model == | ||
Revision as of 02:29, 22 October 2009
Contents |
Abstract
Whether you want to stop a leaking ship's hull, or repair a fractured bone, you need a strong adhesive. Our project aims at producing a new generation of glue. In contrast to most glues, our glue is natural, biodegradable, efficient on wet surfaces and is composed of polysaccharides naturally produced by the Caulobacter crescentus bacterium. Using BioBrickTM standard biological parts, we engineered a synthetic Escherichia coli strain which synthesizes this adhesive material. To improve our expression system, we plan to use a new plasmid stabilization technique, the StabyTM system. This system stabilizes expression plasmid without using antibiotics, which is of major concern in large-scale production of biological materials.
Biological model
Download File:ULB-Report-Model.pdf
Properties
Download File:ULB-Report-Properties.pdf
Mathematical modeling
Download File:ULB-Report-Modeling.pdf
Perspectives
Download File:ULB-Report-Perspectives.pdf
Appendix
Download File:ULB-Report-Appendix.pdf
Bibliography
Download File:ULB-Report-References.pdf
