Team:Tsinghua

   As we know, a relatively significant procedure in gene therapy is to construct a vector to infect target cells and deliver cure gene into them. As a result, the vectors act as a big role. And till now researchers use Adeno-associated viruses did a good job, but the problems of high cost and low production of the virus have been not solved. This is why we attempt to build a highly production carrier in the bacteria. We transform the structure genes of the phage into the bacteria with specific chimera genes attach to the structural genes. We attempt to simulate the Adeno-associated viruses by the phage, for they share the similar structure. And we attach the fiber to the phage to enhance the transformation efficiency.