Team:HKUST/Project
From 2009.igem.org
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# coupled production of chemical attractant | # coupled production of chemical attractant | ||
- | #: Attractant production would be achieved by induced over-expression of an aromatic amino-transferase, an endogenous yeast metabolic enzyme that can catalyze a reaction to yield a volatile insect attractant — 2-phenylethanol, when the downstream signal from the GPCR is activated. | + | #: Attractant production would be achieved by induced over-expression of an aromatic amino-transferase, an endogenous yeast metabolic enzyme that can catalyze a reaction to yield a volatile insect attractant — [http://en.wikipedia.org/wiki/Phenethyl_alcohol 2-phenylethanol], when the downstream signal from the GPCR is activated. |
# production of pest killing toxin | # production of pest killing toxin |
Revision as of 13:22, 12 September 2009
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SynBIOLOGICAL BUG BUSTERInsect pests have been posing threats to human health and the agricultural industry worldwide. To tackle this problem, pesticides and synthetic chemicals were deployed in the past decades; yet abusive use of these chemicals could lead to severe environmental problems. As an alternative strategy to cope with the deteriorating situation, we aim to engineer a novel yeast strain that could detect, attract and eliminate pests. We envision that it would become a substitute for pesticides in the future. Three Parts of the Project
ContributionOur vision is that this project can be applied in both basic scientific research and industrial application. It is going to serve as a modeling system to screen for GPCRs that bind to certain ligands. It will also mark the start of creating yeast strain that would help curb specific insect vectors, such as mosquitoes and cockroaches. Our system will be easy to maintain at low cost. Thus, it is likely that it will benefit under-developed countries where economic incentive is essential for adopting environmental friendly alternatives of pesticides. As a result, this project provides a viable solution to a better environment for our future generations. |