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Team:Valencia/Simulations
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| - | On the other hand, '''cardiomyocytes''' have a different response to an electrical stimulus, as now our “input” function is different: unlike neurons, its plasma membrane is held at a high voltage for a few hundred milliseconds. | + | On the other hand, '''cardiomyocytes''' have a '''different response''' to an electrical stimulus, as now our “input” '''voltage function''' is different: unlike neurons, its plasma membrane is held at a high voltage for a few hundred milliseconds. |
[[Image:Voltage_muscle.jpg|540px|center]] | [[Image:Voltage_muscle.jpg|540px|center]] | ||
| + | [[Image:Calcium_muscle.jpg|560px|center]] | ||
Revision as of 18:29, 13 September 2009
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Simulations
Before simulating how intracellular calcium concentration changes in time, we have approximated the excitatory post-synaptic potential (our "input" function in neurons) as follows:
Then, taking into account all the factors listed in Our Model (Calcium current through VDCCs, Calcium Buffering and Calcium pumps), the result of simulating free intracellular calcium concentration after the electrical stimulation in neurons is this:
On the other hand, cardiomyocytes have a different response to an electrical stimulus, as now our “input” voltage function is different: unlike neurons, its plasma membrane is held at a high voltage for a few hundred milliseconds.
