Team:ULB-Brussels

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<h2>Glue synthesis using <i>E. Coli</i></h2>
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Our subject consists in the production of a strong biological adhesive material. We have decided to tackle the problem by drawing inspiration from the substance naturally produced by Caulobacter crescentus. This bacterium, found in many aquatic environments, synthesises a glue and is then able to stick on nearly all substrates. Our aim is to create a new strain of the famous Escherichia coli that will synthesise this adhesive material and subsequently to try to collect it. </p>
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                        Our subject consists in the production of a strong biological adhesive material. We have decided to tackle the problem by taking inspiration from the substance naturally produced by <i>Caulobacter crescentus</i>. This bacteria, found in many aquatic environments, synthesizes a glue and is then able to stick on nearly all substrates. Our aim is to create a new strain of the famous <i>Escherichia coli</i> that will synthesize this adhesive material and subsequently to try to collect it.
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This project would cover a broad field of applications. This glue is natural, biodegradable, efficient on wet surfaces and has an incomparable resistance (up to 3 times better than super glue).</p>
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                        This project would cover a broad field of applications. This glue is natural, biodegradable, efficient on wet surfaces and has an incomparable resistance (up to 3 times better than a current super glue). Therefore there are multiple prospects and applications that could take advantage of our adhesive material. For example, this glue could be used in the medical field as surgical adhesives for fractured bones, superficial injury or also for dental implant. On boatyards to repair cracked hulls of ships as well.
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<p> Therefore there are multiple prospects and applications which could take advantage of our adhesive material. It could for example be used in the medical field as surgical adhesive for fractured bones, superficial injury or also for dental implant. On boatyards to repair cracked hulls of ships as well
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Revision as of 06:50, 20 September 2009


Days before the Jamboree

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Glue synthesis using E. Coli

Our subject consists in the production of a strong biological adhesive material. We have decided to tackle the problem by drawing inspiration from the substance naturally produced by Caulobacter crescentus. This bacterium, found in many aquatic environments, synthesises a glue and is then able to stick on nearly all substrates. Our aim is to create a new strain of the famous Escherichia coli that will synthesise this adhesive material and subsequently to try to collect it.

This project would cover a broad field of applications. This glue is natural, biodegradable, efficient on wet surfaces and has an incomparable resistance (up to 3 times better than super glue).

Therefore there are multiple prospects and applications which could take advantage of our adhesive material. It could for example be used in the medical field as surgical adhesive for fractured bones, superficial injury or also for dental implant. On boatyards to repair cracked hulls of ships as well

Synthèse de colle au moyen de E. Coli

Le sujet que nous avons choisi d’explorer consiste en la production d’un matériau adhésif biologique. Nous avons décidé d’approcher le problème en exploitant la substance produite naturellement par Caulobacter crescentus. Cette bactérie, présente dans de nombreux milieux aquatiques, synthétise cette glue pour s’accrocher à divers type de substrats et former un biofilm. Notre but est de parvenir à faire synthétiser ce matériau par la célèbre Escherichia coli et de le récupérer.

Ce procédé promet de nombreux avantages quand on sait qu’il s’agira d’une colle non toxique, biodégradable, compatible avec des surfaces mouillées et d’une force d’adhésion incomparable (jusqu’à 3 fois la force d’une super glue actuelle).

Les perspectives et applications sont nombreuses, notamment dans le domaine médical où cette colle pourrait être utilisée comme adhésif chirurgical dans la réparation de fractures ou de blessures superficielles ainsi que des implants dentaires ou encore dans le domaine naval pour la réparation de fissures sur les coques de bateaux.

Klebersynthese unter Verwendung von E. Coli

Das Thema, das zu erforschen wir gewählt haben, besteht in der Herstellung eines biologischen Klebestoffes. Diesem Problem wollten wir uns dadurch nähern, indem wir beschlossen, die von dem Bakterium Caulobacter crescentus natürlicherweise produzierte Substanz zu nutzen. Dieses Bakterium, das in verschiedenartigem wässrigen Milieu vorkommt, produziert durch Bildung eines Biofilms diesen Klebstoff, um an unterschiedlichen Oberflächen haften zu können. Unser Ziel besteht nun darin, zu erreichen, dieses Material durch die berühmte Escherichia coli Bakterien synthetisieren zu lassen, und sie anschließend wiederzugewinnen.

Dieses Verfahren verspricht zahlreiche Vorteile, wenn man weiß, dass es sich um einen nicht toxischen, biologisch abbaubaren Klebstoff handeln wird, der auch auf feuchten Oberflächen haftet und eine unvergleichbare Klebekraft besitzt.( bis zu 3 Mal so stark wie die aktuellen Kleber).

Die Perspektiven und Einsatzmöglichkeiten sind vielfältig, insbesondere im medizinischen Bereich, wo dieser Kleber in der Frakturversorgung denkbar wäre. Ein weiterer Anwendungsbereich wäre der Bootsbau zur Reparatur von Schiffsrümpfen.

使用大腸桿菌來制造強力膠

我們所選擇這個主題是為了生產一種生物粘合劑材料。我們決定利用新月柄桿菌(Caulobacter crescentus)以它所產生的自然粘合物質來解決這個問題。

這種,在水生環境發現的細菌,為了緊緊的守住各種基板產生了"超級膠",以形成生了物膜。

我們的目標是由著名大腸桿菌(E.Coli)合成這種天然材料。 這將會是一個無毒的,生物可分解的膠水,可符合濕表面和傭有獨一無二的附著力量(比起目前人工合成的最強的膠水強三倍)。

前景和應用有很多,特別是在醫學方面於修復骨折,補牙以及外科手術用的粘合劑 甚至能修復船體的微小裂縫。