Team:Illinois/Modeling
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sRNA regulation is a post-transcription regulation mechanism in which the mRNA transcript is degraded before it can be translated or preventing further translation. Traditionally regulation via sRNA is faster acting than transcription factors because there is no delay due to translation and protein folding.[[modeling_resources|[1]]] For this reason, sRNAs are often found to regulate stress and environmental responses. For example, the sRNA, SgrS regulates PtsG, coding for two protein subunits EIIB and EIIC which are involved in the glucose phosphate stress response. [[modeling_resources|[2]]] | sRNA regulation is a post-transcription regulation mechanism in which the mRNA transcript is degraded before it can be translated or preventing further translation. Traditionally regulation via sRNA is faster acting than transcription factors because there is no delay due to translation and protein folding.[[modeling_resources|[1]]] For this reason, sRNAs are often found to regulate stress and environmental responses. For example, the sRNA, SgrS regulates PtsG, coding for two protein subunits EIIB and EIIC which are involved in the glucose phosphate stress response. [[modeling_resources|[2]]] | ||
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[[Image:sRNAdegradationmodel.png|center|400px]] | [[Image:sRNAdegradationmodel.png|center|400px]] | ||
<P align=right>[[modeling_resources|[1]]] | <P align=right>[[modeling_resources|[1]]] | ||
</P> | </P> | ||
Questions about our Wiki page? Please email Dave Korenchan at [mailto:korench1@illinois.edu korench1@illinois.edu]. | Questions about our Wiki page? Please email Dave Korenchan at [mailto:korench1@illinois.edu korench1@illinois.edu]. |
Revision as of 00:50, 19 June 2009
Modeling
sRNA regulation is a post-transcription regulation mechanism in which the mRNA transcript is degraded before it can be translated or preventing further translation. Traditionally regulation via sRNA is faster acting than transcription factors because there is no delay due to translation and protein folding.[1] For this reason, sRNAs are often found to regulate stress and environmental responses. For example, the sRNA, SgrS regulates PtsG, coding for two protein subunits EIIB and EIIC which are involved in the glucose phosphate stress response. [2]
Questions about our Wiki page? Please email Dave Korenchan at korench1@illinois.edu.