Team:Valencia/StochasticApproach

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Stochastic approach

At this point, we are going to use stochastic methods in order to study the activation/inactivation of VDCCs. Unlike deterministic model, the voltage-dependent conductance for the calcium channels is now given by:

Stoc1.jpg

Where the quotient QCa/NCa (number of calcium channels in open state / total number of calcium channels) means the activation variable and g ̅_Ca is the maximum calcium conductance. Each calcium channel is a Markov process with some voltage-dependent transition rates. The kinetic scheme is the following: