"
Team:KULeuven/Modeling/Key Antikey
From 2009.igem.org
Key Lock Antikey
Overview
The Key and Antikey system performs a subtraction of the blue light signal and the vanillin receptor signal. The result controls the vanillin production. The biology behind the subtraction involves the annealing of complementary RNA strands, the Key and the Antikey. This reaction is favoured over the reaction between the Key and the Lock leading to vanillin synthesis. In this way we try to perform the subtraction before inducing production of vanillin.
This biological equivalent of a subtraction can only yield a positive number, so one can only subtract a small from a big amount. Because we can only actively produce vanillin, we have to subtract the measured quantity of vanillin, the amount of anti-key produced by the vanillin receptor from the wanted quantity of vanillin, the amount of key produced by the blue light sensor.
Models
