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From 2009.igem.org

WILD-TYPE MOLECULAR MODEL

WTM simulate crucial reactions and events in the life cycle of phage T7:

• Insertion and translocation of phage's DNA at different times

Phage's DNA is arranged in three classes of genes depending on their positions on the genome, T7 genome is translocated into the cell between 6 to 10 minutes after attachment, so this order and timing drives the phage's development.

• Trancription of phage's polycistronic mRNAs

Transcription of different T7 polycistronic mRNAs occurs only if its coding DNA segment is available in the cell, in this way early phage's mRNAs are present before late mRNAs given that DNA responsible for them is inserted at early stages.

• Translation of phage's mRNAs into proteins

• T7 DNA replication
• Procapsid Assembly
• DNA packaging and final assembly

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