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Team:Michigan/Safety
From 2009.igem.org
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Safety Concerns
This page is used to address the questions posed on the iGEM Safety page:
- Would any of your project ideas raise safety issues in terms of researcher safety, public safety, or environmental safety?
Environmental safety is a huge concern for us. Just as we don't want toluene soil contamination finding its way into water supplies, we don't want our device replicating in the environment when its job of metabolizing the toluene is done, or if it migrates away from the toluene contamination. That's why we are engineering toluene-sensitive suicide mechanisms into our device to destroy it in the absence of toluene. Before it can actually be used for environmental cleanup, we would like to engineer a series of redundant kill switches to cover the possibility of loss-of-function mutations in any of the kill-switch mechanisms.
- Is there a local biosafety group, committee, or review board at your institution?
On a national level, our project would need oversight by the EPA and perhaps other governmental regulatory agencies. On a more local scale, we had a conversation with Dr. Mike Imperiale from the U of M Medical School Department of Microbiology and Immunology about biosafety and biosecurity, and where he thought synthetic biology is and will be going in terms of biosafety and biosecurity.
- What does your local biosafety group think about your project?
