Team:Minnesota/Modeling

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Contents

Our Modeling Goals

Computational Tools

Synthetic Biology Software Suite (SynBioSS)

The entire software suite can be found via the SynBioSS [http://synbioss.sourceforge.net home page].

SynBioSS Designer

SynBioSS Designer is an application for the automatic generation of sets of biomolecular reactions. This software allows a user to input the molecular parts involved in gene expression and regulation (e.g. promoters, transcription factors, ribosomes, etc.) The software then generates complete networks of reactions that represent transcription, translation, regulation, induction and degradation of those parts. To facilitate the creation of detailed kinetic models of synthetic gene networks composed of BioBricks, we have adapted SynBioSS Designer to automatically generate a kinetic model from a construct composed entirely of BioBricks. A NetCDF or SBML file is generated for simulations.

Our goal for this year's iGEM competition is to improve the user interface for SynBioSS be...