Team:Osaka/COLOR
From 2009.igem.org
COLOR
Overview
Under construction
Object
Under construction
Implement
Under construction
Future Work
Color gradation
We plan the genetic circuit which gradually changes cell color. This gene circuit indicates bellow. This is an application of our signal circuit. Signal system includes 2 distinct groups of parts: 'Senders' and 'Receivers'. The specific promoter in the receiver cells is activated by receiving the AHL signal from the sender cells. (More detail)
On this application circuit, the gene coding different color protein from initial color, CI lambda protein gene, and AHL protein gene are on downstream of AHL-activated promoter. CI lambda protein is the repressor of CI promoter which regulates the initial color protein. Therefore, when the signal is received, the cell gradually starts expression of the new color protein and stops expression of initial color protein. In addition, the receiver cells have roles as sender cells against same receiving cell. The signal is conveyed from the cell to the cell. As a result cell color gradually changes.