"
Team:EPF-Lausanne/Modeling
From 2009.igem.org
(Difference between revisions)
| Line 26: | Line 26: | ||
---- | ---- | ||
<br> | <br> | ||
| - | + | ||
==To do== | ==To do== | ||
;- Model allosteric interactions between LOVTAP & TrpR: | ;- Model allosteric interactions between LOVTAP & TrpR: | ||
Revision as of 12:20, 30 July 2009
Contents |
To do
- - Model allosteric interactions between LOVTAP & TrpR
- What will be done:
- - Model of LOVTAP in dark phase
- - Model of LOVTAP in light phase
- - Characterize how the J-alpha helix changes
- - Model structural changes that enhance the switch feature of LOVTAP e.g. in dark phase: really weak interaction between LOVTAP and the corresponding DNA sequence, in light phase: strong binding of LOVTAP on DNA.
- - Between Light state and Dark State
- - RMS between light state and dark state
- - length between the two arms N C
- - only cytochrome with interactions in light state and dark state
To envisage
- Molecular mutational assay
