Team:HKU-HKBU/modeling

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A bacterium can be thought of as a truck travelling along an expressway. If it is free of loading, the truck feels very limited frictional force from the environment, and will be moving at a very high speed. On the other hand, if the truck is heavily loaded with tons of coals, the frictional force will increase linearly. As a result, the truck will have a much lower maximum speed. However, in both situations, the power of the truck remains the same because of the property of the engine. So is the same for bacteria. The power supplied by the motor of the flagella is kept a constant, regardless of the “working condition”, namely whether pushing a motor or not. Thus, the 1st assumption is thought to be reasonable.  
A bacterium can be thought of as a truck travelling along an expressway. If it is free of loading, the truck feels very limited frictional force from the environment, and will be moving at a very high speed. On the other hand, if the truck is heavily loaded with tons of coals, the frictional force will increase linearly. As a result, the truck will have a much lower maximum speed. However, in both situations, the power of the truck remains the same because of the property of the engine. So is the same for bacteria. The power supplied by the motor of the flagella is kept a constant, regardless of the “working condition”, namely whether pushing a motor or not. Thus, the 1st assumption is thought to be reasonable.  
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The 2nd one is taken from the fluid-dynamics, saying that friction is proportional to the cross sectional area for small objects with slow motion. The motor and the bacteria have a size of [[Image:HKU-HKBU_modeling_10_-4_m.png‎]] and [[Image:HKU-HKBU_modeling_10_-6_m.png‎]] respectively, both falling into the region of "small objects". The low speed of a bacteria, [[Image:HKU-HKBU_modeling_10_-5_m_s.png‎]], also fits into the "slow motion" condition. Therefore, the 2nd assumption is believed to be suitable in our case.
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The 2nd one is taken from the fluid-dynamics, saying that friction is proportional to the cross sectional area for small objects with slow motion. The motor and the bacteria have a size of ~ [[Image:HKU-HKBU_modeling_10_-4.png‎]]m and ~ [[Image:HKU-HKBU_modeling_10_-6.png‎]]m respectively, both falling into the region of "small objects". The low speed of a bacteria, ~ [[Image:HKU-HKBU_modeling_10_-5.png‎]]m/s, also fits into the "slow motion" condition. Therefore, the 2nd assumption is believed to be suitable in our case.
==Calculation of Rotational Velocity==
==Calculation of Rotational Velocity==
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We start out by calculating the power of a single bacterium first. Under freely swimming condition, a bacterium can move at a maximum speed of [[Image:HKU-HKBU_modeling_v0.png‎]] ([[Image:HKU-HKBU_modeling_v0.png‎]] [[Image:HKU-HKBU_modeling_10_-5_m_s.png]]). If the friction coefficient is [[Image:HKU-HKBU_modeling_k0.png‎]], then the friction is given by
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We start out by calculating the power of a single bacterium first. Under freely swimming condition, a bacterium can move at a maximum speed of [[Image:HKU-HKBU_modeling_v0.png‎]] ([[Image:HKU-HKBU_modeling_v0.png‎]] ~ [[Image:HKU-HKBU_modeling_10_-5.png]]m/s). If the friction coefficient is [[Image:HKU-HKBU_modeling_k0.png‎]], then the friction is given by
[[Image:HKU-HKBU_modeling_f0.png‎]] = [[Image:HKU-HKBU_modeling_k0.png‎]][[Image:HKU-HKBU_modeling_v0.png‎]][[Image:HKU-HKBU_modeling_f_cheZ.png‎]]
[[Image:HKU-HKBU_modeling_f0.png‎]] = [[Image:HKU-HKBU_modeling_k0.png‎]][[Image:HKU-HKBU_modeling_v0.png‎]][[Image:HKU-HKBU_modeling_f_cheZ.png‎]]

Revision as of 03:44, 14 October 2009

Modeling

Theriotical analysis of the process gives us a quantitative insight into the process. We consider a motor having its simplest shape, i.e. a single lamina with a vertical axis in the middle.

Assumptions

This situation can be analytically solved on the basis of the following assumptions:

  1. power of a bacteria is kept a constant;
  2. friction coefficient of a small object undergoing slow motion is proportional to the cross sectional area;

Let us take a look at the validity of the above assumptions.

A bacterium can be thought of as a truck travelling along an expressway. If it is free of loading, the truck feels very limited frictional force from the environment, and will be moving at a very high speed. On the other hand, if the truck is heavily loaded with tons of coals, the frictional force will increase linearly. As a result, the truck will have a much lower maximum speed. However, in both situations, the power of the truck remains the same because of the property of the engine. So is the same for bacteria. The power supplied by the motor of the flagella is kept a constant, regardless of the “working condition”, namely whether pushing a motor or not. Thus, the 1st assumption is thought to be reasonable.

The 2nd one is taken from the fluid-dynamics, saying that friction is proportional to the cross sectional area for small objects with slow motion. The motor and the bacteria have a size of ~ HKU-HKBU modeling 10 -4.pngm and ~ HKU-HKBU modeling 10 -6.pngm respectively, both falling into the region of "small objects". The low speed of a bacteria, ~ HKU-HKBU modeling 10 -5.pngm/s, also fits into the "slow motion" condition. Therefore, the 2nd assumption is believed to be suitable in our case.

Calculation of Rotational Velocity

We start out by calculating the power of a single bacterium first. Under freely swimming condition, a bacterium can move at a maximum speed of HKU-HKBU modeling v0.png (HKU-HKBU modeling v0.png ~ HKU-HKBU modeling 10 -5.pngm/s). If the friction coefficient is HKU-HKBU modeling k0.png, then the friction is given by

HKU-HKBU modeling f0.png = HKU-HKBU modeling k0.pngHKU-HKBU modeling v0.pngHKU-HKBU modeling f cheZ.png

Here, HKU-HKBU modeling f cheZ.png is a function of expression level of CheZ: if CheZ is fully expressed, the bacteria speed should be maximized, correspondingly HKU-HKBU modeling f cheZ.png = 1. On the other hand, if CheZ is completely knocked out, bacteria should lose the swimming ability. Thus, HKU-HKBU modeling f cheZ.png = 0 corresponds to this case.

Hence, the power is

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