Team:HKUST

From 2009.igem.org

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{{HKUST_iGEM_09|
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==BUG BUSTER==
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[[Image:Gut_flora_color.png|right|thumb|200px|Engineered gut flora]]
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The human gut houses a diverse collection of microorganisms, with important implications for the health and welfare of the host. We aim to engineer a member of this microbial community to provide innovative medical treatments. Our work focuses on four main areas: (1) pathogen defense either by expression of [[Team:Caltech/Project/Phage_Pathogen_Defense|<font style="color:#BB4400">pathogen-specific bacteriophage</font>]] or by targeted bursts of [[Team:Caltech/Project/Oxidative_Burst|<font style="color:#BB4400">reactive oxygen species</font>]]; (2) prevention of birth defects by [[Team:Caltech/Project/Vitamins|<font style="color:#BB4400">folate over-expression</font>]] and delivery; (3) treatment of [[Team:Caltech/Project/Lactose_intolerance|<font style="color:#BB4400">lactose intolerance</font>]] by cleaving lactose to allow absorption in the large intestine; and (4) [[Team:Caltech/Project/Population_Variation|<font style="color:#BB4400">regulation</font>]] of these three treatment functions to produce renewable subpopulations specialized for each function. Our research demonstrates that synthetic biology techniques can be used to modify naturally occurring microbial communities for applications in biomedicine and biotechnology.
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This is a template page. READ THESE INSTRUCTIONS.
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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You <strong>MUST</strong> have a team description page, a project abstract, a complete project description, and a lab notebook. PLEASE keep all of your pages within your teams namespace. 
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[[Testing page]]
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For more details, please see our [[Team:HKUST/Project|<font style="color:#BB4400">project</font>]] page.
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[[Image:HKUST.jpg|left|frame|HKUST picture]]
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
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|[[Image:Example_logo.png|200px|right|frame]]
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''Tell us more about your project.  Give us background.  Use this is the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
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|[[Image:Team.png|right|frame|Your team picture]]
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|align="center"|[[Team:HKUST | Team Example]]
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<!--- The Mission, Experiments --->
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
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!align="center"|[[Team:HKUST|Home]]
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!align="center"|[[Team:HKUST/Team|The Team]]
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!align="center"|[[Team:HKUST/Project|The Project]]
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!align="center"|[[Team:HKUST/Parts|Parts Submitted to the Registry]]
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!align="center"|[[Team:HKUST/Modeling|Modeling]]
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!align="center"|[[Team:HKUST/Notebook|Notebook]]
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(''Or you can choose different headings.  But you must have a team page, a project page, and a notebook page.'')
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--[[User:Tonyho2009|Tonyho2009]] 06:19, 20 August 2009 (UTC)
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Revision as of 06:11, 26 August 2009

HKUST.gif

iGEM 2009



Home

People

Project Details

Protocols

Lab Notebook

Completed Systems

Biosafety

Support


BUG BUSTER

File:Gut flora color.png
Engineered gut flora

The human gut houses a diverse collection of microorganisms, with important implications for the health and welfare of the host. We aim to engineer a member of this microbial community to provide innovative medical treatments. Our work focuses on four main areas: (1) pathogen defense either by expression of pathogen-specific bacteriophage or by targeted bursts of reactive oxygen species; (2) prevention of birth defects by folate over-expression and delivery; (3) treatment of lactose intolerance by cleaving lactose to allow absorption in the large intestine; and (4) regulation of these three treatment functions to produce renewable subpopulations specialized for each function. Our research demonstrates that synthetic biology techniques can be used to modify naturally occurring microbial communities for applications in biomedicine and biotechnology.


For more details, please see our project page.