Team:KULeuven/Modelling/Vanillin Receptor

From 2009.igem.org

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(Vanillin diffusion)
(Vanillin diffusion)
 
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== Overview ==
== Overview ==
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The vanillin receptor senses the vanillin concentration outside the cell. This information is needed to create the feedback loop to control vanillin synthesis. Under influence of vanillin, Vir A gets autophosphorylated and phosphorylates on its turn Vir G. Vir G triggers the transcription of Anti-key.  
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The vanillin receptor senses the vanillin concentration outside the cell. This information is needed to create the feedback loop to control vanillin synthesis. Under influence of vanillin, Vir A gets autophosphorylated and phosphorylates on its turn Vir G. Vir G then triggers the transcription of Anti-key.  
[[image:Biologie_vanillin_receptor.png|center]]
[[image:Biologie_vanillin_receptor.png|center]]
[[image:Biologie_antikey.png|center]]
[[image:Biologie_antikey.png|center]]
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==Models==
==Models==
[[image:Vanillin_receptor.png|600px|center]]
[[image:Vanillin_receptor.png|600px|center]]
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==Vanillin diffusion==
==Vanillin diffusion==
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Because VirA is a senses the vanillin concentration in the cytoplasm, we showed that the extracellular concentration equals the intracellular concentration of vanillin for all our purposes. [https://2009.igem.org/vanillin_sensing.pdf presentation]
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Because VirA senses the vanillin concentration in the cytoplasm, we showed that the extracellular concentration equals the intracellular concentration of vanillin for all our purposes. [https://2009.igem.org/Image:Vanillin_sensing.pdf vanillin_sensing]
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[[Image:Viravirg.JPG|rigth|thumb|425px|VirA is a transmembrane sensory protein kinase that phosphorylates VirG, it's triggered by phenols, monosaccharides and acid]]
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[[Image:Viravirg.JPG|center|thumb|425px|VirA is a transmembrane sensory protein kinase that phosphorylates VirG. It's triggered by phenols, monosaccharides and acid]]

Latest revision as of 14:22, 20 August 2009

Contents

Vanillin Sensor

Overview

The vanillin receptor senses the vanillin concentration outside the cell. This information is needed to create the feedback loop to control vanillin synthesis. Under influence of vanillin, Vir A gets autophosphorylated and phosphorylates on its turn Vir G. Vir G then triggers the transcription of Anti-key.

Biologie vanillin receptor.png
Biologie antikey.png

Models

Vanillin receptor.png

Vanillin diffusion

Because VirA senses the vanillin concentration in the cytoplasm, we showed that the extracellular concentration equals the intracellular concentration of vanillin for all our purposes. vanillin_sensing

VirA is a transmembrane sensory protein kinase that phosphorylates VirG. It's triggered by phenols, monosaccharides and acid