Team:LCG-UNAM-Mexico

From 2009.igem.org

(Difference between revisions)
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Menu Bar 1
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+
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+
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-
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+
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM2,
-
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+
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-
.thrColHybHdr #mainContent { zoom: 1; padding-top: 15px; }
+
}
 +
/*...............................................................................................*/
 +
/*
 +
Menu Bar 1
 +
Drop-Down Menu #2
 +
Side Menu #3
 +
*/
 +
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 +
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 +
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 +
                            Keep it sync with the drop-down menu width. */
 +
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 +
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM3,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu#MB1-DDM2-SM3,
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div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM3 li a,
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 +
/*...............................................................................................*/
 +
 
</style>
</style>
-
<![endif]--></head>
+
<body>
 +
<div id="header">
 +
<OBJECT classid="clsid:D27CDB6E-AE6D-11cf-96B8-444553540000" codebase="http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab#version=6,0,40,0" WIDTH="900" HEIGHT="207" id="https://static.igem.org/mediawiki/igem.org/d/de/Banner_lcg.swf"><PARAM NAME=movie VALUE="https://static.igem.org/mediawiki/igem.org/d/de/Banner_lcg.swf"><PARAM NAME=quality VALUE=high><PARAM NAME=bgcolor VALUE=#FFFFFF><EMBED href="/support/flash/ts/documents/myFlashMovie.swf" quality=high bgcolor=#FFFFFF WIDTH="550" HEIGHT="400" NAME="myMovieName" ALIGN="" TYPE="application/x-shockwave-flash" PLUGINSPAGE="http://www.macromedia.com/go/getflashplayer"></EMBED></OBJECT> </div>
 +
<div class='MenuBar' id="navi">
 +
<ul>
 +
<li>
 +
<a href="https://2009.igem.org/Team:LCG-UNAM-Mexico" style="color: white">Home
 +
<!--[if gt IE 6]><!--></a><!--<![endif]-->
 +
<!--[if lt IE 7]><table border="0" cellpadding="0" cellspacing="0"><tr><td><![endif]-->
 +
<!--[if lte IE 6]></td></tr></table></a><![endif]-->
 +
</li>
 +
<li>
 +
<a href="https://2008.igem.org/Team:Heidelberg/Team" style="color: white">Team<!--[if gt IE 6]><!--></a><!--<![endif]-->
 +
<!--[if lt IE 7]><table border="0" cellpadding="0" cellspacing="0"><tr><td><![endif]-->
 +
<ul class="DropDownMenu" id="MB1-DDM6">
 +
<li><a href="https://2009.igem.org/Team:LCG-UNAM-Mexico"><span><span>Overview</span></span></a></li>
 +
<li><a href="https://2009.igem.org/Team:LCG-UNAM-Mexico"><span><span>Advisors</span></span></a></li>
 +
<li><a href="https://2009.igem.org/Team:LCG-UNAM-Mexico"><span><span>Undergrads</span></span></a></li>
 +
</ul>
 +
<!--[if lte IE 6]></td></tr></table></a><![endif]-->
 +
</li>
 +
<li>
 +
<a href="https://2009.igem.org/Team:LCG-UNAM-Mexico" style="color: white">Project<!--[if gt IE 6]><!--></a><!--<![endif]-->
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    <h1>iGem Team: UNAM</h1>
 
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    <p>Team Members:</p>
 
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    <p>-Osbaldo Rsendis<br />
 
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      -Adrian Granados<br />
 
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      -Laura Gomez<br />
 
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      -Enrique Paz<br />
 
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      -Abraham Avelar<br />
 
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      -Soto Gutierrez<br />
 
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      -Enrique Quintana<br />
 
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      -Willy Garcia<br />
 
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      -Martin del -Castillo<br />
 
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      -Uriel Urquiza<br />
 
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      -Arturo Velarde<br />
 
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      -Minerva  Trejo<br />
 
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      -Fernando Montano<br />
 
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    -Libertad Pantoja</p>
 
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<p>Check out our school:</p>
 
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    <p><a href="www.lcg.unam.mx">-LCG</a><br />
 
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      <a href="www.ccg.unam.mx">-Center of Genomic Sciences</a><br />
 
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      <a href="www.unam.mx">-UNAM</a></p>
 
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<p>&nbsp;</p>
 
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<p>&nbsp;</p>
 
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    <h1> Main Content </h1>
 
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    <p>Bacteriophage infection represents an interesting process in science and industry. The idea of being able to contend at a population level with such  infections is the main motivation of the development of our project. </p>
 
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    <p>We plan to  modify an Escherichia coli phage in order to deliver genetic material codifying  for a construction against other phages, taking advantage of some of their own properties!!! The purpose of this construction is to make a bacterial  to fight back against the spreading of some phage by triggering on  a cellular death response when a cell encounters a specific component of the  phage. Such response will be faster than the formation process of viral  particles preventing the death of the bacterial population. </p>
 
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    <p>This population  resistance can be seen as a sort of &quot;vaccine&quot; that will hold back the process of  infection. The design of the delivery system includes the use the P4 phage and  its auxiliary genes present in the P2 helper phage. In the case of the &quot;vaccine&quot;  construct, the cellular death response will be induced by the presence of T3 or  T7 RNA polymerases which will also turn on the transcription of toxines used for  the degradation of DNA and RNA to stop the phage´s genetic material from  assembling and scattering in the environment. </p>
 
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    <p>Furthermore, we will implement a  stochastic population model based on the basic properties of the bacterial cells  and the phages such as movement, reproduction, etc., this will allow us to  simulate the infection processes and quantify the efficiency of our system. A  possible extention of the system includes the expansion of an AHL signal through  the quorum sensing system of Vibrio fischeri in which the population will be  &quot;warned&quot; to prepare against the viral infection in the presence of T3 or T7. </p>
 
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    <h2>About us </h2>
 
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    <p>Hi, welcome to our site! We are students from the undergraduate program in  Genomic Sciences which is part of the National Autonomous University of Mexico.  We are working on the official version of the wiki. Here you will find advances  and general information about our project.<br />
 
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      Here are some links:<br />
 
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      <br />
 
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      <a href="www.lcg.unam.mx">LCG web site</a><br />
 
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      <a href="www.ccg.unam.mx">Center For  Genomic Sciences</a><br />
 
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    <a href="www.unam.mx">UNAM</a></p>
 
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=='''The Project'''==
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Bacteriophage infection represents an interesting process in science and industry. The idea of being able to contend at a population level with such infections is the main motivation of the development of our project.
 +
 
 +
We plan to modify an Escherichia coli phage in order to deliver genetic material codifying for a construction against other phages, taking advantage of some of their own properties!!! The purpose of this construction is to make a bacterial to fight back against the spreading of some phage by triggering on a cellular death response when a cell encounters a specific component of the phage. Such response will be faster than the formation process of viral particles preventing the death of the bacterial population.
 +
 
 +
This population resistance can be seen as a sort of "vaccine" that will hold back the process of infection. The design of the delivery system includes the use the P4 phage and its auxiliary genes present in the P2 helper phage. In the case of the "vaccine" construct, the cellular death response will be induced by the presence of T3 or T7 RNA polymerases which will also turn on the transcription of toxines used for the degradation of DNA and RNA to stop the phage´s genetic material from assembling and scattering in the environment.
 +
 
 +
Furthermore, we will implement a stochastic population model based on the basic properties of the bacterial cells and the phages such as movement, reproduction, etc., this will allow us to simulate the infection processes and quantify the efficiency of our system. A possible extention of the system includes the expansion of an AHL signal through the quorum sensing system of Vibrio fischeri in which the population will be "warned" to prepare against the viral infection in the presence of T3 or T7.
 +
 
 +
==About us==
 +
Hi, welcome to our site! We are students from the undergraduate program in Genomic Sciences which is part of the National Autonomous University of Mexico. We are working on the official version of the wiki. Here you will find advances and general information about our project.
 +
 
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==News==
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-Sadly we have no news, but stay in touch!!!!
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==Sponsors==
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[[image:Ccg_logo.png|center|100px|https://static.igem.org/mediawiki/2009/7/71/Ccg_logo.png]]
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<p style="text-align: center;">[http://www.ccg.unam.mx Centro de Ciencias Genomicas]</p>
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[[image:Lcg_logo.png|center|100px|https://static.igem.org/mediawiki/2009/e/ef/Lcg_logo.png]]
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<p style="text-align: center;">[http://www.lcg.unam.mx Genomic Sciences Undergraduate program]</p>
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[[image:Unam.gif|center|100px|https://static.igem.org/mediawiki/2009/a/a1/Unam.gif UNAM]]
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<p style="text-align: center;">[http://www.unam.mx/]</p>
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!align="center"|[[Team:LCG-UNAM-Mexico|Home]]
 
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!align="center"|[[Team:LCG-UNAM-Mexico/Team|The Team]]
 
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!align="center"|[[Team:LCG-UNAM-Mexico/Project|The Project]]
 
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!align="center"|[[Team:LCG-UNAM-Mexico/Parts|Parts Submitted to the Registry]]
 
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!align="center"|[[Team:LCG-UNAM-Mexico/Modeling|Modeling]]
 
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!align="center"|[[Team:LCG-UNAM-Mexico/Notebook|Notebook]]
 
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Revision as of 04:05, 18 August 2009


The Project

Bacteriophage infection represents an interesting process in science and industry. The idea of being able to contend at a population level with such infections is the main motivation of the development of our project.

We plan to modify an Escherichia coli phage in order to deliver genetic material codifying for a construction against other phages, taking advantage of some of their own properties!!! The purpose of this construction is to make a bacterial to fight back against the spreading of some phage by triggering on a cellular death response when a cell encounters a specific component of the phage. Such response will be faster than the formation process of viral particles preventing the death of the bacterial population.

This population resistance can be seen as a sort of "vaccine" that will hold back the process of infection. The design of the delivery system includes the use the P4 phage and its auxiliary genes present in the P2 helper phage. In the case of the "vaccine" construct, the cellular death response will be induced by the presence of T3 or T7 RNA polymerases which will also turn on the transcription of toxines used for the degradation of DNA and RNA to stop the phage´s genetic material from assembling and scattering in the environment.

Furthermore, we will implement a stochastic population model based on the basic properties of the bacterial cells and the phages such as movement, reproduction, etc., this will allow us to simulate the infection processes and quantify the efficiency of our system. A possible extention of the system includes the expansion of an AHL signal through the quorum sensing system of Vibrio fischeri in which the population will be "warned" to prepare against the viral infection in the presence of T3 or T7.

About us

Hi, welcome to our site! We are students from the undergraduate program in Genomic Sciences which is part of the National Autonomous University of Mexico. We are working on the official version of the wiki. Here you will find advances and general information about our project.


News

-Sadly we have no news, but stay in touch!!!!

Sponsors

https://static.igem.org/mediawiki/2009/7/71/Ccg_logo.png

Centro de Ciencias Genomicas

https://static.igem.org/mediawiki/2009/e/ef/Lcg_logo.png

Genomic Sciences Undergraduate program

https://static.igem.org/mediawiki/2009/a/a1/Unam.gif UNAM

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