Team:LCG-UNAM-Mexico:Population

INTRODUCTION TO POPULATION MODEL

Bacteria-phage interaction essentially is a fight between two POPULATIONS for survival. Although we modified E. coli at molecular level in order to defend itself against certain phages, our ultimate goal is that E. coli can contend against infection at population level. For this reason we decided to simulate, at population level, phage infection and the effectiveness of our genetic circuit.

For this purpose, we use three different approaches:

• Modelling population dynamics with a system of differential equations.
• Spatial agent-based model.
• Modeling bacteria behaviour and Bacteriophage infection using Cellular Automata.