Team:McGill/Project

From 2009.igem.org

(Difference between revisions)
 
(10 intermediate revisions not shown)
Line 1: Line 1:
-
{|align="justify"
 
-
|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
 
-
|[[Image:Example_loo.png|200px|right]]
 
-
|-
 
-
|
 
-
''Tell us more about your project.  Give us background.  Use this is the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
 
-
|[[Image:Team.png|right]]
 
-
|-
 
-
|
 
-
|align="center"|[[Team:McGill2 | Team Example 2]]
 
-
|}
 
-
 
<html>
<html>
<body>
<body>
<center>
<center>
-
<img src="https://static.igem.org/mediawiki/2009/9/9c/Mcgill09Banner.png" width="780" height="55" usemap="#bannermap">
+
<br/>
 +
 
 +
<img src="https://static.igem.org/mediawiki/2009/d/d5/Mcgill09BannerMod.PNG" width="950" height="250" usemap="#bannermap" id="navbar">
<map id="bannermap" name="bannermap">
<map id="bannermap" name="bannermap">
<area shape="rect"  
<area shape="rect"  
-
coords="0,0,129,55"  
+
coords="0,0,720,200"  
alt="Home"
alt="Home"
href="https://2009.igem.org/Team:McGill">
href="https://2009.igem.org/Team:McGill">
<area shape="rect"  
<area shape="rect"  
-
coords="130,0,260,55"  
+
coords="720,80,900,120"
 +
alt="Home"
 +
href="http://www.mcgill.ca/">
 +
 
 +
<area shape="rect"
 +
coords="0,200,170,250"
 +
alt="Team"
 +
href="https://2009.igem.org/Team:McGill">
 +
 
 +
<area shape="rect"
 +
coords="171,200,317,250"  
alt="Team"
alt="Team"
href="https://2009.igem.org/Team:McGill/Team">
href="https://2009.igem.org/Team:McGill/Team">
<area shape="rect"  
<area shape="rect"  
-
coords="261,0,391,55"  
+
coords="318,200,468,250"  
alt="Project"
alt="Project"
href="https://2009.igem.org/Team:McGill/Project">
href="https://2009.igem.org/Team:McGill/Project">
<area shape="rect"  
<area shape="rect"  
-
coords="392,0,521,55"  
+
coords="469,200,658,250"  
alt="Notebook"
alt="Notebook"
href="https://2009.igem.org/Team:McGill/Notebook">
href="https://2009.igem.org/Team:McGill/Notebook">
<area shape="rect"  
<area shape="rect"  
-
coords="522,0,652,55"  
+
coords="659,200,807,250"  
alt="Results"
alt="Results"
href="https://2009.igem.org/Team:McGill/Results">
href="https://2009.igem.org/Team:McGill/Results">
<area shape="rect"  
<area shape="rect"  
-
coords="623,0,780,55"  
+
coords="808,0,950,250"  
alt="Sponsors"
alt="Sponsors"
href="https://2009.igem.org/Team:McGill/Sponsors">
href="https://2009.igem.org/Team:McGill/Sponsors">
Line 54: Line 54:
</html>
</html>
-
== '''Overall project''' ==
+
=='''Project Goals'''==
 +
Our interest in the dependence of separation distance in activation-inhibition intercellular signaling stems from the possibility of observing oscillations in chemical concentrations over time. This work will not only give us a better understanding of how natural biological systems operate but could also lead to the design of a novel type of biological sensor.
-
Your abstract
+
Imagine a sensor composed of a lawn of bacteria, which under normal conditions are all fluorescing at steady state. However once the system is exposed to a foreign substrate (substance to be detected), the dynamics of the system suddenly switch from steady state to oscillatory, which can be observed and noted by a technician.
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
== Project Details==
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
=== Part 2 ===
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
=== The Experiments ===
+
 +
This idea is still in the planning stages. We have begun exploring this system through two approaches: mathematical and microbiological. We have developed a partial differential equation based model in order to gain insight into the natural dynamics of the system as well as how they vary with perturbations to parameters. In parallel, we have engineered a microbiological system in order to begin carrying out experiments to validate our modeling results. The following pages describe our progress in these two themes.
 +
<html>
 +
</map>
 +
</center>
 +
<br/>
-
=== Part 3 ===
+
<p>
 +
  <table width="100%" border="0">
 +
  <tr>
 +
     
 +
      <td><div align="center">
 +
      <p><a href="https://2009.igem.org/Team:McGill/Modeling" target="_blank"><img    src="https://static.igem.org/mediawiki/2009/8/89/Mcgill09eqn.png" width="300" height="200" /></a></p>
 +
      </div>
 +
      </td>
 +
      <td><div align="center">
 +
      <p><a href="https://2009.igem.org/Team:McGill/Experimental" target="_blank"><img src="https://static.igem.org/mediawiki/2009/e/e5/Mcgill09exp.png" width="300" height="200" /></a></p>
 +
      </div></td>
 +
     
 +
</tr>
 +
<tr>
 +
        <td><div align="center"><p><a href="https://2009.igem.org/Team:McGill/Modeling" target="_blank"><b>Modeling</b></a></p></div></td>
 +
        <td><div align="center"><p><a href="https://2009.igem.org/Team:McGill/Experimental" target="_blank"><b>Experimental</b></a></p></div></td>
-
== Results ==
+
</tr>
 +
</table>
 +
</p>

Latest revision as of 07:33, 21 October 2009


Home Home Team Team Project Notebook Results Sponsors

Project Goals

Our interest in the dependence of separation distance in activation-inhibition intercellular signaling stems from the possibility of observing oscillations in chemical concentrations over time. This work will not only give us a better understanding of how natural biological systems operate but could also lead to the design of a novel type of biological sensor.

Imagine a sensor composed of a lawn of bacteria, which under normal conditions are all fluorescing at steady state. However once the system is exposed to a foreign substrate (substance to be detected), the dynamics of the system suddenly switch from steady state to oscillatory, which can be observed and noted by a technician.

This idea is still in the planning stages. We have begun exploring this system through two approaches: mathematical and microbiological. We have developed a partial differential equation based model in order to gain insight into the natural dynamics of the system as well as how they vary with perturbations to parameters. In parallel, we have engineered a microbiological system in order to begin carrying out experiments to validate our modeling results. The following pages describe our progress in these two themes.