Team:Michigan/Modeling

From 2009.igem.org

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<ul>
<ul>
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<li> this is a list element </li>
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<li> This is in order to balance antiholin and holin levels without repression </li>
 +
<li> ''This can be tuned so that timing of cell death works out'' </li>
 +
<li> Set antiholin production rate to that of holin in the absence of repression </li>
 +
<li> Put this through the transcription and translation equations to obtain production rate </li>
</ul>
</ul>

Revision as of 22:12, 20 October 2009


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HOME THE TEAM THE PROJECT MODELING REGISTRY PARTS NOTEBOOK SAFETY

Kill switch topology for modeling.jpg


Cell Growth/Death

Transcription of Repressor:

Transcription of Lysozyme and Holin:

Repression of Lysozyme and Holin Transcription

Production of Repressor

Production of Proteins

Assumptions

Can set γA equal to rate of production of holin in the case that all operating sites are free

  • This is in order to balance antiholin and holin levels without repression
  • This can be tuned so that timing of cell death works out
  • Set antiholin production rate to that of holin in the absence of repression
  • Put this through the transcription and translation equations to obtain production rate