Team:NTU-Singapore/Notebook/Brainstorming
From 2009.igem.org
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** mimic the maslinic effect to the carcinogenic cells? | ** mimic the maslinic effect to the carcinogenic cells? | ||
** surface markers? | ** surface markers? | ||
+ | * trap parasites in host cells by disabling the protease | ||
+ | ** Can we remove the trap parasites? | ||
+ | ** Terminate parasites? | ||
+ | * genetic modified bacteria that have anticoagulant properties. | ||
+ | * eczema relief | ||
+ | * bacteria to treat gangrene | ||
+ | ** to eat up dead tissues | ||
+ | ** bac to deliver growth factors | ||
+ | * collagen producing bacteria | ||
+ | * bacteria that absorbs cholesterol | ||
+ | * constipation pill | ||
+ | * synthesis specific growth factors | ||
+ | * bacteria tt produce PDGF | ||
+ | * using bacteria to breakdown blockage in blood vessels | ||
+ | * malaria vaccine | ||
+ | ** forcibly experesses a certain gene and create a vaccine against it | ||
+ | ** to prove the concept | ||
+ | * cancer treatment-colon cancer(CA marker) | ||
+ | ** fusion protein to signal the expression of perforin (e coli as NKC) | ||
+ | * streptococcus vaccine | ||
+ | * p-falciparum gene expression stabilization ; Malaria | ||
+ | * intestinal vaccine delivery | ||
+ | * bac to target the larvae; Malaria | ||
+ | *To separate Tamoxifen (possibly a chiral drug) by uptake the drugs into modified E Coli and bind it to the receptor inside the bacteria. | ||
+ | |||
+ | |||
+ | == Biosensor == | ||
+ | |||
+ | * biosensor that sense the present of allergen and release drugs to prevent allergenic response | ||
+ | * Mimic allergy response-to determine allergen? | ||
+ | * fingerprint detection | ||
+ | * Can cells response to magnetic fields? | ||
+ | ** Bird GPS ?? | ||
+ | ** magnetic field biosensor | ||
+ | * biosensor to detect cancer | ||
+ | |||
+ | |||
+ | == Environmental == | ||
+ | |||
+ | * E coli to detect toxins in food and flu strain in animals. | ||
+ | * Biomask | ||
+ | ** For absorption | ||
+ | * create a water purifying system that recognize and trap toxic | ||
+ | ** to uptake salt and others- sea water purification | ||
+ | * bacteria producing water for the use of photosynthesis so that plants can grow well in dry area | ||
+ | ** is it possible to construct water using certain metabolism pathway? | ||
+ | |||
+ | |||
+ | == Signalling == | ||
+ | |||
+ | * Multi-color display according to inputs | ||
+ | ** to improve signal inputs | ||
+ | * DNA methylation as memory storage | ||
+ | * suffocate the cells | ||
+ | * baccine | ||
+ | * To construct guiding E Coli that guide pathogenic bacteria to a region of toxin/UV light. | ||
+ | |||
+ | |||
+ | ==Application == | ||
+ | |||
+ | * bacterial barometer | ||
+ | * fill up crack | ||
+ | * dust repel | ||
+ | * microscopic spring-using spirobac | ||
+ | * To construct a Sound sensing bacteria | ||
+ | |||
+ | |||
+ | ==Modeling== | ||
+ | |||
+ | * modeling the trend of evolution of flu viruses | ||
+ | |||
+ | |||
+ | ==Bioproduction== | ||
+ | |||
+ | * Methanol in E-coli | ||
+ | |||
+ | |||
Revision as of 21:21, 21 October 2009
Experiment Timeline
Health & medicine
- Create an insulin delivery system which response to low glucose level or time controlled release
- Vitamin synthesis?
- Hinder carcinogenics
- Maslinic acid (olive skin)-tritrepenoid compound
- Can we study anti-tumoral and apoptotic effect of this compound?
- E coli to interfere in the carcinogenic pathways
- mimic the maslinic effect to the carcinogenic cells?
- surface markers?
- trap parasites in host cells by disabling the protease
- Can we remove the trap parasites?
- Terminate parasites?
- genetic modified bacteria that have anticoagulant properties.
- eczema relief
- bacteria to treat gangrene
- to eat up dead tissues
- bac to deliver growth factors
- collagen producing bacteria
- bacteria that absorbs cholesterol
- constipation pill
- synthesis specific growth factors
- bacteria tt produce PDGF
- using bacteria to breakdown blockage in blood vessels
- malaria vaccine
- forcibly experesses a certain gene and create a vaccine against it
- to prove the concept
- cancer treatment-colon cancer(CA marker)
- fusion protein to signal the expression of perforin (e coli as NKC)
- streptococcus vaccine
- p-falciparum gene expression stabilization ; Malaria
- intestinal vaccine delivery
- bac to target the larvae; Malaria
- To separate Tamoxifen (possibly a chiral drug) by uptake the drugs into modified E Coli and bind it to the receptor inside the bacteria.
Biosensor
- biosensor that sense the present of allergen and release drugs to prevent allergenic response
- Mimic allergy response-to determine allergen?
- fingerprint detection
- Can cells response to magnetic fields?
- Bird GPS ??
- magnetic field biosensor
- biosensor to detect cancer
Environmental
- E coli to detect toxins in food and flu strain in animals.
- Biomask
- For absorption
- create a water purifying system that recognize and trap toxic
- to uptake salt and others- sea water purification
- bacteria producing water for the use of photosynthesis so that plants can grow well in dry area
- is it possible to construct water using certain metabolism pathway?
Signalling
- Multi-color display according to inputs
- to improve signal inputs
- DNA methylation as memory storage
- suffocate the cells
- baccine
- To construct guiding E Coli that guide pathogenic bacteria to a region of toxin/UV light.
Application
- bacterial barometer
- fill up crack
- dust repel
- microscopic spring-using spirobac
- To construct a Sound sensing bacteria
Modeling
- modeling the trend of evolution of flu viruses
Bioproduction
- Methanol in E-coli