Team:NTU-Singapore/Notebook/Brainstorming

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Revision as of 21:21, 21 October 2009 by Sjee (Talk | contribs)

Experiment Timeline


Health & medicine

  • Create an insulin delivery system which response to low glucose level or time controlled release
  • Vitamin synthesis?
  • Hinder carcinogenics
    • Maslinic acid (olive skin)-tritrepenoid compound
    • Can we study anti-tumoral and apoptotic effect of this compound?
    • E coli to interfere in the carcinogenic pathways
    • mimic the maslinic effect to the carcinogenic cells?
    • surface markers?
  •  trap parasites in host cells by disabling the protease
    • Can we remove the trap parasites?
    • Terminate parasites?
  • genetic modified bacteria that have anticoagulant properties.
  • eczema relief
  • bacteria to treat gangrene
    • to eat up dead tissues
    • bac to deliver growth factors
  • collagen producing bacteria
  • bacteria that absorbs cholesterol
  • constipation pill
  • synthesis specific growth factors
  • bacteria tt produce PDGF
  • using bacteria to breakdown blockage in blood vessels
  • malaria vaccine
    •  forcibly experesses a certain gene and create a vaccine against it
    • to prove the concept
  • cancer treatment-colon cancer(CA marker)
    • fusion protein to signal the expression of perforin (e coli as NKC)
  • streptococcus vaccine
  • p-falciparum gene expression stabilization ; Malaria
  • intestinal vaccine delivery
  • bac to target the larvae; Malaria
  • To separate Tamoxifen (possibly a chiral drug) by uptake the drugs into modified E Coli and bind it to the receptor inside the bacteria.


Biosensor

  • biosensor that sense the present of allergen and release drugs to prevent allergenic response
  • Mimic allergy response-to determine allergen?
  •  fingerprint detection
  •  Can cells response to magnetic fields?
    • Bird GPS ??
    • magnetic field biosensor
  •  biosensor to detect cancer


Environmental

  • E coli to detect toxins in food and flu strain in animals.
  • Biomask
    •  For absorption
  • create a water purifying system that recognize and trap toxic
    • to uptake salt and others- sea water purification
  • bacteria producing water for the use of photosynthesis so that plants can grow well in dry area
    • is it possible to construct water using certain metabolism pathway?


Signalling

  • Multi-color display according to inputs
    • to improve signal inputs
  • DNA methylation as memory storage
  • suffocate the cells
  • baccine
  • To construct guiding E Coli that guide pathogenic bacteria to a region of toxin/UV light.


Application

  • bacterial barometer
  • fill up crack
  • dust repel
  • microscopic spring-using spirobac
  • To construct a Sound sensing bacteria


Modeling

  • modeling the trend of evolution of flu viruses


Bioproduction

  • Methanol in E-coli





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