Team:NYMU-Taipei/Project

From 2009.igem.org

(Difference between revisions)
(Sales Pitch)
(Design)
Line 20: Line 20:
* Signal Transduction after viruses attach
* Signal Transduction after viruses attach
* Removal of the ViroTerminator itself and the virus
* Removal of the ViroTerminator itself and the virus
 +
 +
 +
This research is aimed to design a method to capture the specific membrane protein of virus.  For certain virus, we design the biological parts, the conjugated viral receptor, to bind onto it and trigger LPS for removal.  Also a backup evacuation, oscillator triggered removal, will act when it catches no virus for a certain time.
 +
== Delegation ==
== Delegation ==
Our subteams for experimentation and research were split in this manner:
Our subteams for experimentation and research were split in this manner:

Revision as of 14:12, 30 September 2009


Contents

Project Overview

Our ViroTerminator is made Safe for the bloodstream. When it is injected into the bloodstream, our ViroTerminator passively lies around in the blood stream letting viruses attach to it by using its 4 receptors: CD4 (for HIV), Integrin (for various viruses), Sialic Acid (for Influenza), Antibodies (specific chosen viruses). After enough viruses attach to it, or after a certain amount of time elapses, it removes itself from the bloodstream by calling macrophages to eat it up.

Sales Pitch

ViroCatcher

Want to be virus-free[1]? Our ViroCatcher destroys viruses ranging from short-term viruses such as the flu, to long term viruses such as HIV. Buy our ViroTerminator today!

Small print:
[1] Free as in free beer. Free from viruses that the ViroTerminator is designed to act upon.

Design

Our design was split into 4 parts:

  • Making our machine safe
  • Attaching receptors to catch the virus
  • Signal Transduction after viruses attach
  • Removal of the ViroTerminator itself and the virus


This research is aimed to design a method to capture the specific membrane protein of virus. For certain virus, we design the biological parts, the conjugated viral receptor, to bind onto it and trigger LPS for removal. Also a backup evacuation, oscillator triggered removal, will act when it catches no virus for a certain time.

Delegation

Our subteams for experimentation and research were split in this manner:

  • Safe E. coli: Making our machine safe.
  • Cellular receptors
    • CD4 (HIV)
    • Integrin (various)
    • Sialic Acid (Influenza)
    • Antibodies (specific)
  • Signal Transduction
  • Removal
  • Testing