Team:TUDelft/Brainstorm

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===MO muscle===
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===MicroOrganism muscle===
* make a group of cells contract
* make a group of cells contract

Revision as of 20:23, 6 May 2009


Brainstorm Area


Interesting Links



Interesting Papers (provided by Domenico)




Brainstorm Ideas


Impulse Signal

  • one suggestion (by Federico C.) from the idea exchange was to create a self-destructing plasmid, which would express once and than destroy itself with a restriction endonuclease in its code.


Water Soluble Vitamin Production

  • produce Vitamins B and C.


Stop Quorum Signalling -> Quenching AHL

  • halogenated furanones [2] [3] decrease binding activity of LuxR.
  • Bonnie Bassler's research, inhibit quorum signaling with molecules structurally similar to AHL. Her recent TED Talk.


Biological Isotope Separation

  • is it even possible?
  • according to this book in section 2.6.5. [4], both chlorella algae and E.coli have isotope enrichment properties (hydrogen, deuterium). no references given.
  • possible applications: remove radioactive isotopes from body (cancer treatments), separate heavy water from ocean water, remove carbon 14 and potassium 40 from body/food.
  • another paper is Bioseparation of Lithium Isotopes by Using Microorganisms, Sakaguchi, Takashi | Tomita, Osamu, Resource and Environmental Biotechnology [Resour. Environ. Biotechnol.]. Vol. 3, no. 2-3, pp. 173-182. 2000. havent found a copy online.


Saltwater Purification

  • + heavy metal extraction
  • diatoms
  • Dead Sea organisms


Xylitol production

  • already attempted, see [5]


Melatonin Compensation

  • compensate the reduction in melatonin levels caused by the invention of electrical lights
  • would need to implement melatonin detection, synthesis, and a clock


New Antibiotic Cassettes

  • Biobricks exist for Ampicillin, Kanamycin, Chloramphenicol, and Tetracycline.
  • New biobricks needed (see TK:Wishlist), integrate into larger project?
  • Cationic peptides, Rhodostreptomycins [6]


Paper Based Microfluidics with bacteria

  • use light sensor and output hydrophobic/hydrophilic chemicals that can coat the cellulose in the paper placed on an agar plate


Close proximity phage expression

  • once a cell is close enough to a target, produce phages and explode


Anti-Venom System

  • inject bacteria after being bitten
  • sense which venom and produce proper anti-venom


Birth Control Yoghurt

  • attacks sperm
  • animal use


Buoyant Bacteria

  • for metal extraction from old mines or ocean


Excrement Degradation Bacteria

  • dog excrements degrades quickly
  • can be used in as excrement degrader instead of waste tank in portable toilets or deodorizing excrements in chemical toilets


Additional Processing of Excretion for Energy

  • Zero Growth -> convert everything to product


Targeted Delivery

  • use THC for medical benefits without any psychoactive effects


microRNA and P53

  • inhibit miRNA to increase activity of tumor-suppressor gene p53
  • needs targeted delivery system


Synchronization -> Flashing Colony

  • synchronized flashing
  • covalent modification


Sensor Reporter Spatially Displaced

Kalman Filter

  • integrate into larger project


Stopping a Cytokine storm

  • something which could break the feedback loop in a cytokine storm


MicroOrganism muscle

  • make a group of cells contract


 

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