Team:Tsinghua

From 2009.igem.org

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<!-- *** What falls between these lines is the Alert Box!  You can remove it from your pages once you have read and understood the alert *** -->
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{{Tsinghua/Header}}
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<div id="box" style="width: 700px; margin-left: 137px; padding: 5px; border: 3px solid #000; background-color: #fe2b33;">
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<html xmlns="http://www.w3.org/1999/xhtml">
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<div id="template" style="text-align: center; font-weight: bold; font-size: large; color: #f6f6f6; padding: 5px;">
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<style type="text/css">
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This is a template page. READ THESE INSTRUCTIONS.
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a.index_link:link{
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color:#FFF;
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<div id="instructions" style="text-align: center; font-weight: normal; font-size: small; color: #f6f6f6; padding: 5px;">
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font:Arial, Helvetica, sans-serif;
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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font-size:medium;
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text-decoration:none;
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<div id="warning" style="text-align: center; font-weight: bold; font-size: small; color: #f6f6f6; padding: 5px;">
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}
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You <strong>MUST</strong> have a team description page, a project abstract, a complete project description, and a lab notebook.  PLEASE keep all of your pages within your teams namespace. 
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a.index_link:visited{
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color:#FFF;
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font:Arial, Helvetica, sans-serif;
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a.index_link:active{
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font:Arial, Helvetica, sans-serif;
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#overview {
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{|align="justify"
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<body>
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|You can write a background of your team here. Give us a background of your team, the members, etc. Or tell us more about something of your choosing.
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<table width="950" height="400" border="0" cellpadding="0" cellspacing="0">
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|[[Image:Example_logo.png|200px|right|frame]]
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  <tr>
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|-
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  <td><center></center></td>
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  </tr>
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''Tell us more about your project. Give us background. Use this is the abstract of your project. Be descriptive but concise (1-2 paragraphs)''
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  <tr>
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|[[Image:Team.png|right|frame|Your team picture]]
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  <td><table width="950" height="65" border="0" cellpadding="0" cellspacing="0">
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|-
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    <tr align="left" valign="top">
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      <td width="131"><img src= "http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_01.gif" width="337" height="65" alt=""></td>
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|align="center"|[[Team:Tsinghua | Team Example]]
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      <td width="871">&nbsp;</td>
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|}
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    </tr>
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  </table>
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<!--- The Mission, Experiments --->
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    <table width="900" height="56" border="0" cellpadding="0" cellspacing="0">
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
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      <td width="337"><img src="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_03.gif" width="337" height="56" alt=""></td>
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!align="center"|[[Team:Tsinghua|Home]]
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      <td width="83"><img src="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_04.gif" width="83" height="56" alt=""></td>
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!align="center"|[[Team:Tsinghua/Team|The Team]]
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      <td width="530" align="right" valign="bottom"><table width="205" border="0" cellspacing="0" cellpadding="0">
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!align="center"|[[Team:Tsinghua/Project|The Project]]
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        </table></td>
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!align="center"|[[Team:Tsinghua/Parts|Parts Submitted to the Registry]]
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    </tr>
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!align="center"|[[Team:Tsinghua/Modeling|Modeling]]
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</table>
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!align="center"|[[Team:Tsinghua/Notebook|Notebook]]
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<table width="950" height="39" border="0" cellpadding="0" cellspacing="0">
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    <tr align="left" valign="top">
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(''Or you can choose different headingsBut you must have a team page, a project page, and a notebook page.'')
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      <td width="337"><img src="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_08.gif" width="337" height="39" alt=""></td>
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      <td width="83"><img src="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_09.gif" width="83" height="39" alt=""></td>
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          <td width="88.3" bgcolor="#0099FF" class="td_link"><center>
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            <a href="#" class="index_link"><a href="https://2009.igem.org/Team:Tsinghua/Team"
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            class="index_link">Team</a>
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          </center></td>
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          <td width="88.3" bgcolor="#0099FF" class="td_link"><center>
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            <a href="https://2009.igem.org/Team:Tsinghua/Project" class="index_link">Project</a>
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          </center></td>
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          <td width="88.3" bgcolor="#0099FF" class="td_link"><center>
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            <a href="https://2009.igem.org/Team:Tsinghua/Modeling" class="index_link">Modeling</a>
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          </center></td>
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          <td width="88.3" bgcolor="#0099FF" class="td_link"><center>
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            <a href="http://partsregistry.org/cgi/partsdb/pgroup.cgi?pgroup=iGEM2009&group=Tsinghua" class="index_link">Parts</a>
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          </center></td>
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          <td width="88.3" bgcolor="#0099FF" id="td_link"><center><a href="https://2009.igem.org/Team:Tsinghua/ELSI" class="index_link">ELSI</a>
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          </center></td>
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          <td width="88.3" bgcolor="#0099FF" id="td_link"><center><a href="https://2009.igem.org/Team:Tsinghua/Notebook" class="index_link">Notebook</a>
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      <td width="337"><img src="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_17.gif" width="337" height="191" alt=""></td>
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      <td width="83"><img src="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_18.gif" width="83" height="191" alt=""></td>
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      <td width="74"><img src="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_19.gif" width="88" height="191" alt=""></td>
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          <td width="8%" align="left" background="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_21.gif">&nbsp;</td>
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          <td width="92%" align="right" valign="bottom" background="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_21.gif"></td>       
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          <td height="191" colspan="2" align="left" background="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_21.gif"><div id="overview">&nbsp; &nbsp;Since a significant procedure in gene therapy is to construct vectors to infect target cells and deliver cure gene into them,efficent vectors play a big role. And until now researchers using adenoviruses did a good job, but the production of virus suffers from high cost and low output. This is why we attempt to build a highly productive carrier in the bacteria. We transplanted the structure genes of the phage into the bacteria with specific chimera genes attached to the structural genes. We attempt to engineer lambda phage so that it has similar tranfection function as adenoviruses, taking advantage of their similar structures. We attach the engineered fiber from adenoviruses to phages to achieve better transfection efficiency and specificity. At the same time, we use the cosmid in the phage to carry the cure gene. The engineered phage vectors not only have great capability to carry large and multiple genes, but also can cell specific transfection.</div></td>
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  <table width="950" height="37"  border="0" cellpadding="0" cellspacing="0">
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      <td width="337"> <img src="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_24.gif" width="337" height="37" alt=""></td>
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      <td width="613"> <img src="http://www.tsinghua.edu.cn/cic_jsp/qhdwzy/index_images/index_25.gif" width="83" height="37" alt=""></td>
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          <td width="450">
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            <a href="http://www.tsinghua.edu"><img src="https://static.igem.org/mediawiki/2009/5/5f/Thu.jpeg" width="80" height="80"></a>
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            <a href="http://life.tsinghua.edu.cn/image/logo.gif"><img src="http://life.tsinghua.edu.cn/image/logo.gif" width="200" height="80"></a>
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            <a href="https://static.igem.org/mediawiki/2009/d/df/Sponsor_footer_trim.png"><img src="https://static.igem.org/mediawiki/2009/d/df/Sponsor_footer_trim.png" width="1000" height="50"></a>
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</html>

Latest revision as of 14:19, 20 October 2009

 
   Since a significant procedure in gene therapy is to construct vectors to infect target cells and deliver cure gene into them,efficent vectors play a big role. And until now researchers using adenoviruses did a good job, but the production of virus suffers from high cost and low output. This is why we attempt to build a highly productive carrier in the bacteria. We transplanted the structure genes of the phage into the bacteria with specific chimera genes attached to the structural genes. We attempt to engineer lambda phage so that it has similar tranfection function as adenoviruses, taking advantage of their similar structures. We attach the engineered fiber from adenoviruses to phages to achieve better transfection efficiency and specificity. At the same time, we use the cosmid in the phage to carry the cure gene. The engineered phage vectors not only have great capability to carry large and multiple genes, but also can cell specific transfection.