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Contents 1 Introduction 2 Phage production in E.coli 3 Naked Plasmid Vector Production 3.1 Reaction kinetics 4 Headline text

Introduction

Phage production in E.coli

Naked Plasmid Vector Production

One of our team's sub project is the use nakes plasmid binded with a specified protein as the vector of gene therapy DNA. The normal replication process of plasmid will be changed due to the binding of specified protein(in our model,lambda repressor). Considering production of the plasmid protein complex, we want to maxize the amounts of plasmid protein complex, so a balance between the amounts of plasmid and protein is needed. In this model, we want to find out the optimized parameters for this plasmid vector production process.

Reaction kinetics

DNA protein complex’s binding and separating is dynamical process

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