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Team:UCSF/Future Applications
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In the previous sections we have shown you that we can steer cells to new targets, control their speed and attach a payload. Here we describe our vision of what we could do with these engineered cells in the future. | In the previous sections we have shown you that we can steer cells to new targets, control their speed and attach a payload. Here we describe our vision of what we could do with these engineered cells in the future. | ||
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One target for our cells could be '''carcinoid tumors:''' | One target for our cells could be '''carcinoid tumors:''' | ||
* these tumors are located in the '''gut and lungs''' and are often '''malignant''' | * these tumors are located in the '''gut and lungs''' and are often '''malignant''' | ||
| - | * they are small and | + | * they are small and therefore '''hard to find''' |
* they '''secrete high levels of serotonin''' - a neuroactive hormone '''detected by Gi-coupled GPCR''' | * they '''secrete high levels of serotonin''' - a neuroactive hormone '''detected by Gi-coupled GPCR''' | ||
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Our approach could be used to '''engineer a cellular robot''' that: | Our approach could be used to '''engineer a cellular robot''' that: | ||
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or | or | ||
* '''delivers targeted chemotherapeutic drugs''' to kill tumor | * '''delivers targeted chemotherapeutic drugs''' to kill tumor | ||
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[[Image:VISION.jpg|500px|thumb|center|'''VISION:''' We could use our engineered cellular robots to home in on carcinoid tumors to deliver imaging or therapeutic reagents.]] | [[Image:VISION.jpg|500px|thumb|center|'''VISION:''' We could use our engineered cellular robots to home in on carcinoid tumors to deliver imaging or therapeutic reagents.]] | ||
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| + | {| style="color:#333333;background-color:#cccccc;" cellpadding="3" cellspacing="3" border="0" bordercolor="#231f26" width="99%" align="center" | ||
| + | !align="center"|[[Team:UCSF|Home]] | ||
| + | !align="center"|[[Team:UCSF/Team|The Team]] | ||
| + | !align="center"|[[Team:UCSF/Project|The Project]] | ||
| + | !align="center"|[[Team:UCSF/Parts|Parts Submitted to the Registry]] | ||
| + | !align="center"|[[Team:UCSF/Our summer experience|Our summer experience]] | ||
| + | !align="center"|[[Team:UCSF/Notebook|Notebook]] | ||
| + | !align="center"|[[Team:UCSF/Human Practices|Human Practices]] | ||
| + | |} | ||
Latest revision as of 00:49, 21 October 2009
VISION: Example of a possible application
In the previous sections we have shown you that we can steer cells to new targets, control their speed and attach a payload. Here we describe our vision of what we could do with these engineered cells in the future.
One target for our cells could be carcinoid tumors:
- these tumors are located in the gut and lungs and are often malignant
- they are small and therefore hard to find
- they secrete high levels of serotonin - a neuroactive hormone detected by Gi-coupled GPCR
Our approach could be used to engineer a cellular robot that:
- detects serotonin and can chemotax to carcinoid tumors
- delivers imaging reagents (to aid in surgical removal)
or
- delivers targeted chemotherapeutic drugs to kill tumor
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