Team:Utah State/Modeling
From 2009.igem.org
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<td id="nav"><a href="https://2009.igem.org/Team:Utah_State/Project"><font size = 4>PROJECT</font></a></td> | <td id="nav"><a href="https://2009.igem.org/Team:Utah_State/Project"><font size = 4>PROJECT</font></a></td> | ||
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<td id="nav"><a href="https://2009.igem.org/Team:Utah_State/Parts"><font size = 4>BIOBRICKS</font></a></td> | <td id="nav"><a href="https://2009.igem.org/Team:Utah_State/Parts"><font size = 4>BIOBRICKS</font></a></td> | ||
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- | <div align="center"><img src="https://static.igem.org/mediawiki/2009/ | + | <div align="center"><img src="https://static.igem.org/mediawiki/2009/a/a3/ModifiedGraph1.jpg" align = "middle" height="400" style="padding:.5px; border-style:solid; border-color:#999" alt="Figure 3"> </div> |
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<div align="center"><font size="2.5" face="Helvetica, Arial, San Serif" color =#231f20> | <div align="center"><font size="2.5" face="Helvetica, Arial, San Serif" color =#231f20> | ||
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<p class= "class">Simulations for the Tat pathway were run for 3600 seconds (1 hour). The shorter length of simulation relative to the Sec model is used despite having significantly longer protein translocation time because the time-consuming folding step limits the reaction. The results of the ordinary differential equation simulation are shown below in Figure 4. The amount of periplasmic protein is lower than cytoplasmic and folded protein values upon reaching steady state. This is due to the rate-limiting folding step, which also leads to an expected high concentration of folded protein as well. | <p class= "class">Simulations for the Tat pathway were run for 3600 seconds (1 hour). The shorter length of simulation relative to the Sec model is used despite having significantly longer protein translocation time because the time-consuming folding step limits the reaction. The results of the ordinary differential equation simulation are shown below in Figure 4. The amount of periplasmic protein is lower than cytoplasmic and folded protein values upon reaching steady state. This is due to the rate-limiting folding step, which also leads to an expected high concentration of folded protein as well. | ||
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- | <div align="center"><img src="https://static.igem.org/mediawiki/2009/ | + | <div align="center"><img src="https://static.igem.org/mediawiki/2009/d/d2/ModifiedGraph2.jpg" align = "middle" height="400" style="padding:.5px; border-style:solid; border-color:#999" alt="Figure 3"> </div> |
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<div align="center"><font size="2.5" face="Helvetica, Arial, San Serif" color =#231f20> | <div align="center"><font size="2.5" face="Helvetica, Arial, San Serif" color =#231f20> | ||
- | <b>Figure | + | <b>Figure 3.</b> Simulation of protein production and translocation by the Sec pathway |
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Latest revision as of 03:06, 22 October 2009
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